Dengue is a viral infection which is transmitted by the Aedes aegypti mosquito and has four serotypes (DENV-1 to DENV-4). The disease triggers a variety of clinical manifestations, ranging from mild forms without warning signs to severe lifethreatening forms. We present the case of a 5-year-old boy, from the province of Callao, whose first symptoms were fever, headache and general malaise. On the third day, the child had mild abdominal pain and little vomiting; subsequently, abdominal distension, jaundice and choluria. He was admitted to the pediatric intensive care unit being alert and with moderate dehydration, jaundice, edema, distended and tender abdomen, shifting dullness and liver 2 cm below the right costal margin. Complementary tests revealed liver failure, hepatosplenomegaly and pleural effusion in the bases. Using a reactive IgM ELISA, severe dengue was diagnosed, as well as a ...

Monkeypox is a rare disease caused by the monkeypox virus (MPXV). This virus can enter the host through different routes, such as the oropharynx, nasopharynx and intradermal routes, among others. In 2022, an outbreak was reported in which the virus seemed to have mutations that would make it spread more efficiently. We present three cases of monkeypox in a family of eight members. Patient 1, a 32-year-old man, presented with a papule under the left eye, which was hatched manually by his wife. He then developed endophthalmitis associated with fever and headache, in addition to nonpainful vesicular pruritic lesions on the extremities and genitalia. He was eventually clinically diagnosed with monkeypox infection. Patient 2, a 27-year-old woman (wife of patient 1), presented with vesicular and pustular lesions on the chest, extremities and anal area six days after exposure through close cont...

El 9 de febrero de 2024 se cumplieron tres años desde que la vacuna de la empresa Sinopharm fue aplicada por primera vez en el Perú; los profesionales de la salud fueron el primer grupo poblacional en recibirla (1). Este hito ocurrió mientras los peruanos vivían en un contexto de imparable confusión y creciente temor ante el virus SARS-CoV-2, pero con la esperanza de que la ciencia, haciendo gala de sus herramientas, pudiera mostrar a la población la tan ansiada luz al final del túnel pandémico. En el Centro de Investigación de Virología de la Universidad de San Martín de Porres (CIV-USMP) se ha revisado información relevante, tanto a nivel nacional como internacional, y se ha reflexionado sobre los tres años transcurridos desde aquella primera dosis de la vacuna BBIBP-CorV de Sinopharm en nuestro país.