The vaccine against SARS-CoV-2 has demonstrated proven efficacy to control the disease, rare adverse effects due to this therapy are still being studied, some of them renal. It is suggested that an inadequate immune response could be the cause of glomerular diseases associated with vaccination. We describe a 26-year-old patient, with no significant history, received immunity from the SARS-CoV-2 vaccine (Sinopharm), after which he began with proteinuria in the nephrotic range. Proteinuria: 24g in 24 hours. Albumin: 2.36 mg/dl. COVID-19 test negative. Renal biopsy was performed with ultrasound guidance, with anatomopathological result of Focal and Segmental Glomerulosclerosis, tip variant, observing 17 glomeruli. The patient was hospitalized and received immunosuppression with pulses of methylprednisolone, oral prednisone 1mg/kg/day, atorvastatin 20mg/day, antiplatelet therapy with ASA 100...

Carta al editor que resalta la importancia de actualizar los datos de los estudios de ERC en regiones, además de hacer grandes estudios epidemiológicos, las cuales permitirán desarrollar políticas para reducir la prevalencia de la enfermedad renal crónica además de reducir costos al sistema de salud.

Introducción: la enfermedad renal crónica (ERC) es un problema de salud pública en el Perú. El sistema de salud peruano invierte alrededor del 4% de su presupuesto total en financiar solo terapias de hemodiálisis. Objetivo: determinar la comparación de los costos directos entre las terapias de reemplazo renal (TRR). Materiales y métodos: estudio descriptivo de análisis de costos. Se evaluaron los costos de los pacientes en las tres diferentes TRR: trasplante renal, hemodiálisis, diálisis peritoneal de la Red Asistencial Junín del Seguro Social EsSalud. Se analizaron los datos de 213 pacientes. Se calcularon los costos medios. Los datos fueron tomados de la Unidad de Adquisiciones y Costos de la Red Asistencial Junín (RAJ) EsSalud desde el año 2016 al año 2021. Resultados: el trasplante renal en el primer año acarrea un costo de 70 680 soles (US$ 18 123,07), el cual disminu...

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Introduction: Chronic kidney disease (CKD) is a public health problem in Peru. The Peruvian health system spends nearly 4% of its total budget just for paying only hemodialysis therapy. Objective: To determine a comparison of direct costs between kidney replacement therapy options. Materials and methods: This is a descriptive study for cost analysis. Costs for patients when using different modalities of kidney replacement therapy were assessed: renal transplant, hemodialysis, and peritoneal dialysis in Junin Health Network from Peruvian Social Security (EsSalud). Data from 213 patients was analyzed. Mean costs were calculated. Data was taken from the Acquisition and Cost Unit of the Junin Health Network in EsSalud from 2016 to 2021. Results: Renal transplant in the first year costs 70 680 PEN (US$ 18,123.07), and the cost is reduced as years go by. Afterwards, from the second year on the...

Introduction: Chronic kidney disease (CKD) is a public health problem in Peru. The Peruvian health system spends nearly 4% of its total budget just for paying only hemodialysis therapy. Objective: To determine a comparison of direct costs between kidney replacement therapy options. Materials and methods: This is a descriptive study for cost analysis. Costs for patients when using different modalities of kidney replacement therapy were assessed: renal transplant, hemodialysis, and peritoneal dialysis in Junin Health Network from Peruvian Social Security (EsSalud). Data from 213 patients was analyzed. Mean costs were calculated. Data was taken from the Acquisition and Cost Unit of the Junin Health Network in EsSalud from 2016 to 2021. Results: Renal transplant in the first year costs 70 680 PEN (US$ 18,123.07), and the cost is reduced as years go by. Afterwards, from the second year on the...

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Letter to the Editor (without abstract)

A 39-year-old woman, residing at 3,200 meters above sea level, with stage 5 chronic kidney disease and on hemodialysis, who presented an unscheduled pregnancy. During gestation, she was on daily hemodialysis regimen with 21 hours per week, restricted heparin, multidisciplinary management, in addition to high doses of erythropoietin reaching 16,000 IU weekly. At 32 weeks of gestation she underwent emergency cesarean section due to intrauterine growth restriction type III. A male newborn was born APGAR 8-9, weight 1,420 grams, who was transferred to the neonatal intensive care unit. After 30 days, the newborn was discharged, and the mother had a stable and uncomplicated puerperium. This is the first case reported in a pregnant hemodialysis patientliving at high altitude. Due to the complexity of the case, multidisciplinary management was necessary. Further studies of this type of patients ...

En la actualidad, las actividades cotidianas como comprar un producto o servicio y comunicarse con una persona, se realizan de una forma más efectiva a través del uso de una variable indispensable: la tecnología. De esta manera, las personas han desarrollado un estilo de vida innovador que incorpora el uso de dispositivos tecnológicos con el objetivo de facilitar y mejorar la experiencia de realizar actividades diarias relacionadas al entretenimiento, deporte, etc. Por otro lado, se puede observar una demanda de personas que practican deporte amateur donde –en la mayoría de casos- practican fútbol. En ese sentido, se evidencia que en la actualidad la oferta de servicios orientados a las personas que practican fútbol no logra satisfacer las necesidades básicas ni aprovechar la demanda creciente del fútbol amateur. En ese contexto, PichanGO es una plataforma virtual que busca me...

Objective. To describe the prevalence of anemia among patients undergoing chronic hemodialysis treatment in an altitude population (3200 m a.s.l.) in the Department of Junín (Peru). Methods. Observational, retrospective study. Data were taken from the National Dialysis Registry (RENDES, 2021) in the Department of Junín (Peru) and from the medical records of hemodialysis patients of the EsSalud Social Security in the year 2021. The sample population consisted of all patients who constituted the Chronic Hemodialysis Program of the Junín Region. Descriptive data were analyzed in Stata, version 17.0. Results. The prevalence of anemia was 3.9%. Only 5 patients had anemia associated with chronic kidney disease (CKD) (3.9%). Data were collected from 128 patients. 64.8% (n = 83) were male. The main cause of CKD was arterial hypertension (AHT) (37.5%), then type 2 diabetes mellitus (24.2%). Th...

En la actualidad, las actividades cotidianas como comprar un producto o servicio y comunicarse con una persona, se realizan de una forma más efectiva a través del uso de una variable indispensable: la tecnología. De esta manera, las personas han desarrollado un estilo de vida innovador que incorpora el uso de dispositivos tecnológicos con el objetivo de facilitar y mejorar la experiencia de realizar actividades diarias relacionadas al entretenimiento, deporte, etc. Por otro lado, se puede observar una demanda de personas que practican deporte amateur donde –en la mayoría de casos- practican fútbol. En ese sentido, se evidencia que en la actualidad la oferta de servicios orientados a las personas que practican fútbol no logra satisfacer las necesidades básicas ni aprovechar la demanda creciente del fútbol amateur. En ese contexto, PichanGO es una plataforma virtual que busca me...

Introducción: Los pacientes con lupus eritematoso sistémico (LES) presentan una disminución de la actividad de la enfermedad cuando evoluciona a una enfermedad renal crónica (ERC). Se han publicado recaídas de LES en esta etapa en diferentes grupos étnicos, aunque no pacientes hispanos, tradicionalmente asociados a peor pronóstico. Objetivo: Describir los casos de pacientes con ERC en hemodiálisis con diagnóstico de recaída de la enfermedad. Presentación de casos: Se presentan 4 casos, 2 varones y 2 mujeres con una edad promedio de 28 años. Tuvieron un promedio de score de SLEDAI sin criterios renales de 20.25, quienes presentaron exacerbaciones de diferentes características. Todos recibieron tratamiento inmunosupresor y fallecieron 2 pacientes.

Objetivo: Identificar factores relacionados con la supervivencia del injerto renal en pacientes trasplantados. Materiales y métodos: Se analizaron 34 historias clínicas de pacientes trasplantados en el Hospital Nacional Ramiro Prialé Prialé entre enero del 2004 y abril del 2023. Para determinar la supervivencia del injerto se realizó la prueba de Kaplan Meier y la regresión de Cox con el método paso a paso; así mismo, se hizo el análisis univariado y bivariado (chi cuadrado). Resultados: El tiempo medio de supervivencia del injerto hasta el momento del estudio fue de 135,810 meses años con un intervalo de confianza del 95%. La causa predominante de enfermedad renal crónica fue la hipertensión arterial con 85,2%, seguida por la vasculitis con un 8,8%. El 79,4% de los injertos provino de donantes vivos. El tratamiento inmunosupresor más empleado incluyó tacrolimus, prednisona...

Introduction. Percutaneous renal biopsy is one of the procedures that has contributed most to the knowledge of kidney diseases. Our country does not have updated data on this specific topic. Our objective is to report the proportion of different types of primary and secondary glomerulopathies in renal biopsies performed by the Nephrology Service of the National Hospital Dos de Mayo from 2007 to 2016. Methods. Retrospective case series with review of records clinics in the Nephrology Service of the Dos de Mayo National Hospital. The renal biopsies registry of the Nephrology Department was taken from 2007 to 2016. The results of the reports of renal biopsies were reviewed, the results are reported in proportions. Results. 139 kidney biopsies were recorded. In relation to primary glomerulopathies, the most frequent cause reported was focal and segmental glomerulonephritis, then membranoprol...

Coca leaf has been traditionally used for medical purposes and contains high iron levels. Objective: To determine the effect of Erythroxylum coca spp. ethanol extract in iron-deficiency anemia induced by iron-deficient diet in male Holtzman rats. Design: Experimental. Setting: Institute of Pathology Laboratory, Universidad Nacional Mayor de San Marcos. Biologic material: Eighteen weaned male Holtzman rats 16 days old. Interventions: Rats were allocated to three groups of six rats each: a) iron-sufficient group (IS) received 25 g/d of balanced diet for 7 weeks; b) iron-deficient group (ID) received 25 g/d of iron-deficient diet for 7 weeks; and, c) irondeficient/ E. coca extract group (ID-CE) received 25 g/d of iron-deficient diet for 7 weeks, and in the fifth week 18 g/d of E. coca extract were added. Main outcome measures: Serum hemoglobin level, weight and height. Results: At the end o...