Because increasing climatic variability and anthropic pressures have affected the sediment dynamics of large tropical rivers, long-term sediment concentration series have become crucial for understanding the related socioeconomic and environmental impacts. For operational and cost rationalization purposes, index concentrations are often sampled in the flow and used as a surrogate of the cross-sectional average concentration. However, in large rivers where suspended sands are responsible for vertical concentration gradients, this index method can induce large uncertainties in the matter fluxes. Assuming that physical laws describing the suspension of grains in turbulent flow are valid for large rivers, a simple formulation is derived to model the ratio (α) between the depth-averaged and index concentrations. The model is validated using an exceptional dataset (1330 water samples, 249 con...