The report of critical values ​​is considered a necessary practice in clinical pathology laboratories, since its immediate communication determines therapeutic decisions that can save lives. The choice of critical values ​​and the way in which they are reported must be a joint decision between the laboratory specialists and the clinical professionals of each health facility, since they must be integrated into the dynamics of the services involved. Among the critical values ​​that have been chosen for this review, we have included quantitative parameters, whose processing is carried out in automated hematology analyzers, and morphological findings in peripheral blood smears, which are evaluated by trained professionals.

Chronic myeloid leukemia (CML) is a common myeloproliferative disease in adults, characterized by an overproduction of granulocytes in bone marrow as a consequence of the t(9:22)(q34;q11) translocation, known as Philadelphia chromosome. We present a case of CML in a 12-year-old male patient, who was admitted for outpatient care at the Alberto Sabogal Sologuren National Hospital. The clinical and laboratory findings of the case are described. Also, a general presentation of the disease is made and the differences between adult and pediatric CML are discussed, since it is a rare neoplasm in pediatric patients.

Objetivos: El objetivo del estudio es comparar, entre dos grupos de pacientes, una serie de factores clínico- epidemiológicos relacionados a mortalidad: edad, sexo, comorbilidades, tipo de estatus epiléptico y uso de ventilación mecánica. Material y Métodos: El estudio se realizó en el Hospital Cayetano Heredia entre enero de 2012 hasta diciembre de 2014. Incluyó 94 pacientes con el diagnóstico de estatus epiléptico admitidos durante el período establecido. El estudio comparó datos de los supervivientes contra datos de los fallecidos. Se recolectó la información de las historias clínicas en una ficha de datos para la elaboración de una base de datos. Resultados: La mortalidad intrahospitalaria fue de 8,51%. La media de edad   fue de 41,8 años. Las principales etiologías halladas fueron la epilepsia idiopática (28,72%), la neurocisticercosis (14,89%) y la enfermedad c...

Objective: assess five EIA tests aimed to quantify specific antibodies to SARS-CoV-2 and compared to a surrogate viral neutralization for assessing neutralizing antibodies. Methods: We conducted a cross-sectional study during the period from July to October 2020, in which the sera of 96 participants whose ages were between 18 and 65 years were evaluated, all recovered from COVID-19 and obtained between 28 and 212 days after the onset of symptoms. ELISA tests used for testing include measurement of total antibodies (IgG & IgM); IgG antibodies against S protein (IgG S1/S2, IgG S, IgG S-RBD); IgG antibodies against nucleocapsid antigens, and IgM antibodies against S-RBD antigen. Pearson's linear correlation coefficient was used to know the degree of correlation between the values of the viral neutralization antibody titer and the values of the titer level of antibodies evaluated by each of ...