Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity

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The study was to evaluate the essential oil of Erythroxylum coca Lam. var. coca (Coca) - from Quillabamba province, Cusco region and determine its antibacterial activity, and elucidate the same chemical composition by Gas Chromatography / Mass Spectrometry (GC / MS). The plant part used the dried le...

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Detalles Bibliográficos
Autores: Ventura, G., Castro, A., Roque, M., Ruiz, J.
Formato: artículo
Fecha de Publicación:2009
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/3382
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3382
Nivel de acceso:acceso abierto
Materia:Erythroxylum coca
actividad antibacteriana
Staphylococcus aureus
antibacterial activity
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spelling Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activityComposición química del aceite esencial de Erythroxylum coca Lam var. Coca (coca) y evalua­ción de su actividad antibacterianaVentura, G.Castro, A.Roque, M.Ruiz, J.Erythroxylum cocaactividad antibacterianaStaphylococcus aureusErythroxylum cocaantibacterial activityStaphylococcus aureusThe study was to evaluate the essential oil of Erythroxylum coca Lam. var. coca (Coca) - from Quillabamba province, Cusco region and determine its antibacterial activity, and elucidate the same chemical composition by Gas Chromatography / Mass Spectrometry (GC / MS). The plant part used the dried leaves were provided by the National Coca Company ENACO SA, which dealt with a system by steam distillation of water. The essential oil yield was 0.08% v/p and on that physicochemical tests were performed: Miscibility, density and refractive index. In the chemical composition found the following components: Guai-1(5),(11)-diene, t-cadinene, (2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecan-1 -ol, eudesm-4(14)-en-11-ol, hexahydrofarnesil ketone, hexadecanoic acid, phytol, cis-9-octadecenoic and octadecanoic acid. The study of antibacterial activity in vitro, using the method of excavation culture plate at concentrations of 10 and 50% of the oil showed greater activity to Staphylococcus aureus strain ATCC 25923, than against strains of Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis and Pseudomonas aeruginosa ATCC 27853 strain. It was determined that the chemical components of essential oil of Erythroxylum coca Lam. Var coca (Coca) have antibacterial activity against Staphylococcus aureus.El estudio consistió en evaluar el aceite esencial de Erythroxylum coca Lam. var. coca (Coca) – proveniente de la provincia de Quillabamba, región Cusco y determinar su actividad antibacteriana; así mismo, elucidar su composición química por Cromatografía de Gases / Espectrometría de Masa (CG/EM). La parte usada de la planta fueron las hojas secas proporcionadas por la Empresa Nacional de la Coca ENACO S.A., las que se trataron con un sistema de destilación por arrastre con vapor de agua. El rendimiento del aceite esencial fue de 0,08% v/p y en éste se practicaron los ensayos fisicoquímicos: miscibilidad, densidad e índice de refracción. En la composición química se encontraron los siguientes componentes: Guaia-1(5),(11)–diene, t–cadinene, (2E,7R,11R)-3,7,11,15-tetrametil-2-hexadecen-1-ol, eudesm-4(14)-en-11-ol, hexahydrofarnesil cetona, ácido hexadecanoico, fitol, ácido cis-9-octadecenoico y ácido octadecanoico. El estudio de la actividad antibacteriana in vitro, utilizando el método de excavación placa cultivo a concentraciones de 10 y 50% del aceite, mostró mayor actividad a Staphylococcus aureus cepa ATCC 25923, que frente a las cepas de Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis, y Pseudomonas aeruginosa cepa ATCC 27853. Se determinó que los componentes químicos del aceite esencial de Erythroxylum coca Lam. Var coca (Coca) poseen actividad antibacteriana contra Staphylococcus aureus.Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica2009-06-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/338210.15381/ci.v12i1.3382Ciencia e Investigación; Vol. 12 Núm. 1 (2009); 24-28Ciencia e Investigación; Vol. 12 No. 1 (2009); 24-281609-90441561-0861reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3382/4504Derechos de autor 2009 G. Ventura, A. Castro, M. Roque, J. Ruizhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/33822020-04-26T13:49:11Z
dc.title.none.fl_str_mv Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
Composición química del aceite esencial de Erythroxylum coca Lam var. Coca (coca) y evalua­ción de su actividad antibacteriana
title Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
spellingShingle Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
Ventura, G.
Erythroxylum coca
actividad antibacteriana
Staphylococcus aureus
Erythroxylum coca
antibacterial activity
Staphylococcus aureus
title_short Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
title_full Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
title_fullStr Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
title_full_unstemmed Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
title_sort Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
dc.creator.none.fl_str_mv Ventura, G.
Castro, A.
Roque, M.
Ruiz, J.
author Ventura, G.
author_facet Ventura, G.
Castro, A.
Roque, M.
Ruiz, J.
author_role author
author2 Castro, A.
Roque, M.
Ruiz, J.
author2_role author
author
author
dc.subject.none.fl_str_mv Erythroxylum coca
actividad antibacteriana
Staphylococcus aureus
Erythroxylum coca
antibacterial activity
Staphylococcus aureus
topic Erythroxylum coca
actividad antibacteriana
Staphylococcus aureus
Erythroxylum coca
antibacterial activity
Staphylococcus aureus
description The study was to evaluate the essential oil of Erythroxylum coca Lam. var. coca (Coca) - from Quillabamba province, Cusco region and determine its antibacterial activity, and elucidate the same chemical composition by Gas Chromatography / Mass Spectrometry (GC / MS). The plant part used the dried leaves were provided by the National Coca Company ENACO SA, which dealt with a system by steam distillation of water. The essential oil yield was 0.08% v/p and on that physicochemical tests were performed: Miscibility, density and refractive index. In the chemical composition found the following components: Guai-1(5),(11)-diene, t-cadinene, (2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecan-1 -ol, eudesm-4(14)-en-11-ol, hexahydrofarnesil ketone, hexadecanoic acid, phytol, cis-9-octadecenoic and octadecanoic acid. The study of antibacterial activity in vitro, using the method of excavation culture plate at concentrations of 10 and 50% of the oil showed greater activity to Staphylococcus aureus strain ATCC 25923, than against strains of Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis and Pseudomonas aeruginosa ATCC 27853 strain. It was determined that the chemical components of essential oil of Erythroxylum coca Lam. Var coca (Coca) have antibacterial activity against Staphylococcus aureus.
publishDate 2009
dc.date.none.fl_str_mv 2009-06-15
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3382
10.15381/ci.v12i1.3382
url https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3382
identifier_str_mv 10.15381/ci.v12i1.3382
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3382/4504
dc.rights.none.fl_str_mv Derechos de autor 2009 G. Ventura, A. Castro, M. Roque, J. Ruiz
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2009 G. Ventura, A. Castro, M. Roque, J. Ruiz
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica
dc.source.none.fl_str_mv Ciencia e Investigación; Vol. 12 Núm. 1 (2009); 24-28
Ciencia e Investigación; Vol. 12 No. 1 (2009); 24-28
1609-9044
1561-0861
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.7211075
Chemical composition of essential oil Erythroxylum coca Lam var. coca (Coca) and evaluation of its antibacterial activity
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