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artículo
Objectives. To evaluate the association between allergic rhinitis and the degree of pulmonary involvement in patients with COVID-19 and to determine the frequencies of the main variables. Materials and methods. An observational, cross-sectional and analytical study was carried out by reviewing the medical records of patients diagnosed with COVID-19 from the Cayetano Heredia National Hospital between 2020 and 2021. We obtained information regarding the history of allergic rhinitis; pulmonary involvement was assessed by non-contrast tomography results using the chest computed tomography (CT) score. Data regarding sociodemographic and clinical variables was also obtained. Both crude (PR) and adjusted (aPR) prevalence ratios with their respective 95% confidence intervals (CI) were estimated. We also used a generalized linear Poisson family model with log link function and robust variances. R...
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libro
CITIE 2020, enfocado en Educación Digital Post COVID-19, debido al contexto de la pandemia se ha desarrollado de forma virtual. CITIE promueve espacios de diálogo y reflexión entre profesores, gestores e investigadores relacionados con la educación. Esta edición de CITIE ha permitido la socialización de las tendencias e innovaciones que se están manifestando ellos mismos en diversos contextos educativos. En esta ocasión se han realizado 80 manuscritos de los cuales 36 fueron aceptados para presentación, estos se enmarcan en las áreas temáticas de este edición: • Educación digital. • Tendencias en educación. • Innovación educativa. Entendemos que la educación es la única herramienta de cambio en la sociedad y estos espacios de la socialización, como CITIE, favorece este desarrollo.
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artículo
Placental abruption (PA), a pregnancy-related vascular disorder, is a leading cause of maternal and perinatal morbidity and mortality. The success of identifying genetic susceptibility loci for PA, a multi-factorial heritable disorder, has been limited. We conducted a genome-wide association study (GWAS) and candidate gene association study using 470 PA cases and 473 controls from Lima, Peru. Genotyping for common genetic variations (single nucleotide polymorphisms, SNPs) was conducted using the Illumina Cardio-Metabo Chip platform. Common variations in 35 genes that participate in mitochondrial biogenesis (MB) and oxidative phosphorylation (OS) were selected for the candidate gene study. Regression models were fit to examine associations of each SNP with risk of PA. In pathway analyses, we examined functions and functional relationships of genes represented by the top GWAS hits. Genetic...