A Functional Assessment Tool to DistinguishControls From Alzheimer’s Disease in Lima,Peru

• Autores: Custodio, Nilton, Montesinos, Rosa, Chambergo-Michilot, Diego, Herrera-Perez, Eder, Pintado-Caipa, Maritza, Seminario, Wendy, Cuenca, José, Mesía, Laura, Failoc-Rojas, Virgilio E, Diaz, Monica M
• Formato: artículo
• Fecha de Publicación: 2022
• Institución: Universidad Privada Norbert Wiener
• Repositorio: UWIENER-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.uwiener.edu.pe:20.500.13053/6903
• Enlace del recurso: https://hdl.handle.net/20.500.13053/6903; https://doi.org/10.1177/15333175221104354
• Nivel de acceso: acceso abierto
• Materia: alzheimer disease, dementia, neurocognitive disorders, peru, validation study; http://purl.org/pe-repo/ocde/ford#3.03.00

Background:The Alzheimer’s Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functionalassessment tool for patients with Alzheimer’s disease (AD). We evaluated its performance in controls, Peruvians with MCI orAD.Methods:A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment(MCI),ADor cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach’salpha) and validity were assessed.Results:We enrolled 276 individuals (AD: 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressivesymptom differences. Reliability was ideal (ICC: .996), and Cronbach’s alpha was adequate (.937). The ADCS-ADL could notdifferentiate MCI from controls but did differentiateADseverity. The ADCS-ADL correlated highly with nearly all tools.Conclusions:The ADCS-ADL scale is reliable in a population withADin Lima, Peru. Future work may validate a tool forPeruvians with lower educational levels.