Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom

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Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and...

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Detalles Bibliográficos
Autores: Schneider, Francisco S., Starling, Maria C., Duarte, Clara G., Machado de Avila, Ricardo, Kalapothakis, Evanguedes, Silva Suarez, Walter, Tintaya, Benigno, Flores Garrido, Karin, Seraylan Ormachea, Silvia, Yarleque, Armando, Bonilla, César, Chávez-Olórtegui, Carlos
Formato: artículo
Fecha de Publicación:2012
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:UNMSM-Tesis
Lenguaje:inglés
OAI Identifier:oai:cybertesis.unmsm.edu.pe:20.500.12672/27429
Enlace del recurso:https://hdl.handle.net/20.500.12672/27429
https://doi.org/10.1016/j.toxicon.2012.06.018.
Nivel de acceso:acceso abierto
Materia:Bothrops andianus
Serpiente andina
Veneno
https://purl.org/pe-repo/ocde/ford#1.06.03
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network_name_str UNMSM-Tesis
repository_id_str 410
dc.title.none.fl_str_mv Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
title Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
spellingShingle Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
Schneider, Francisco S.
Bothrops andianus
Serpiente andina
Veneno
https://purl.org/pe-repo/ocde/ford#1.06.03
title_short Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
title_full Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
title_fullStr Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
title_full_unstemmed Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
title_sort Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
author Schneider, Francisco S.
author_facet Schneider, Francisco S.
Starling, Maria C.
Duarte, Clara G.
Machado de Avila, Ricardo
Kalapothakis, Evanguedes
Silva Suarez, Walter
Tintaya, Benigno
Flores Garrido, Karin
Seraylan Ormachea, Silvia
Yarleque, Armando
Bonilla, César
Chávez-Olórtegui, Carlos
author_role author
author2 Starling, Maria C.
Duarte, Clara G.
Machado de Avila, Ricardo
Kalapothakis, Evanguedes
Silva Suarez, Walter
Tintaya, Benigno
Flores Garrido, Karin
Seraylan Ormachea, Silvia
Yarleque, Armando
Bonilla, César
Chávez-Olórtegui, Carlos
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Schneider, Francisco S.
Starling, Maria C.
Duarte, Clara G.
Machado de Avila, Ricardo
Kalapothakis, Evanguedes
Silva Suarez, Walter
Tintaya, Benigno
Flores Garrido, Karin
Seraylan Ormachea, Silvia
Yarleque, Armando
Bonilla, César
Chávez-Olórtegui, Carlos
dc.subject.none.fl_str_mv Bothrops andianus
Serpiente andina
Veneno
topic Bothrops andianus
Serpiente andina
Veneno
https://purl.org/pe-repo/ocde/ford#1.06.03
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#1.06.03
description Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and lethality. The Peruvian anti-bothropic anti-venom displays consistent cross-reactivity with B. andianus venom, by ELISA and Western Blotting and is also effective in neutralizing the venom's toxic activities.
publishDate 2012
dc.date.accessioned.none.fl_str_mv 2025-09-19T16:03:35Z
dc.date.available.none.fl_str_mv 2025-09-19T16:03:35Z
dc.date.issued.fl_str_mv 2012-07-14
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.citation.none.fl_str_mv Schneider, F. S., Starling, M. C., Duarte, C. G., Machado de Avila, R., Kalapothakis, E., Silva Suarez, W., Tintaya, B., Flores Garrido, K., Seraylan Ormachea, S., Yarleque, A., Bonilla, C., & Chávez-Olórtegui, C. (2012). Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom. Toxicon, 60(6), 1018-1021. https://doi.org/10.1016/j.toxicon.2012.06.018
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12672/27429
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.toxicon.2012.06.018.
identifier_str_mv Schneider, F. S., Starling, M. C., Duarte, C. G., Machado de Avila, R., Kalapothakis, E., Silva Suarez, W., Tintaya, B., Flores Garrido, K., Seraylan Ormachea, S., Yarleque, A., Bonilla, C., & Chávez-Olórtegui, C. (2012). Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom. Toxicon, 60(6), 1018-1021. https://doi.org/10.1016/j.toxicon.2012.06.018
url https://hdl.handle.net/20.500.12672/27429
https://doi.org/10.1016/j.toxicon.2012.06.018.
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.none.fl_str_mv Vol. 60
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Toxicon
publisher.none.fl_str_mv Toxicon
dc.source.none.fl_str_mv reponame:UNMSM-Tesis
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str UNMSM-Tesis
collection UNMSM-Tesis
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spelling Schneider, Francisco S.Starling, Maria C.Duarte, Clara G.Machado de Avila, RicardoKalapothakis, EvanguedesSilva Suarez, WalterTintaya, BenignoFlores Garrido, KarinSeraylan Ormachea, SilviaYarleque, ArmandoBonilla, CésarChávez-Olórtegui, Carlos2025-09-19T16:03:35Z2025-09-19T16:03:35Z2012-07-14Schneider, F. S., Starling, M. C., Duarte, C. G., Machado de Avila, R., Kalapothakis, E., Silva Suarez, W., Tintaya, B., Flores Garrido, K., Seraylan Ormachea, S., Yarleque, A., Bonilla, C., & Chávez-Olórtegui, C. (2012). Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom. Toxicon, 60(6), 1018-1021. https://doi.org/10.1016/j.toxicon.2012.06.018https://hdl.handle.net/20.500.12672/27429https://doi.org/10.1016/j.toxicon.2012.06.018.Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and lethality. The Peruvian anti-bothropic anti-venom displays consistent cross-reactivity with B. andianus venom, by ELISA and Western Blotting and is also effective in neutralizing the venom's toxic activities.Perú. Universidad Nacional Mayor de San Marcos. Vicerrectorado de Investigación y Posgrado. Proyecto N° B20100301. Perú. Fondo Nacional de Ciencia y Tecnología-Fondecyt. Contrato N° 101-2018- FONDECYT-BM-IADT-AVapplication/pdfengToxiconVol. 60info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/Bothrops andianusSerpiente andinaVenenohttps://purl.org/pe-repo/ocde/ford#1.06.03Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venominfo:eu-repo/semantics/articlereponame:UNMSM-Tesisinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://cybertesis.unmsm.edu.pe/bitstreams/04937baf-7ce9-4a9a-8092-f22df50280da/downloadbb9bdc0b3349e4284e09149f943790b4MD51ORIGINAL1-s2.0-S0041010112005375-main.pdf1-s2.0-S0041010112005375-main.pdfapplication/pdf279795https://cybertesis.unmsm.edu.pe/bitstreams/57c477a0-42ef-4685-a747-fe1c06430f06/downloadc58d147acbc56b0826bdb544c3203f70MD5120.500.12672/27429oai:cybertesis.unmsm.edu.pe:20.500.12672/274292025-09-19 11:03:35.755https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessopen.accesshttps://cybertesis.unmsm.edu.peCybertesis UNMSMcybertesis@unmsm.edu.peTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0IG93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLCB0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZyB0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sIGluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlIHN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yIHB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZSB0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQgdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uIGFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LCB5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZSBjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdCBzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkIHdpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRCBCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUgRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSCBDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZSBzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMgbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=
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Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom
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