Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom

• Autores: Schneider, Francisco S., Starling, Maria C., Duarte, Clara G., Machado de Avila, Ricardo, Kalapothakis, Evanguedes, Silva Suarez, Walter, Tintaya, Benigno, Flores Garrido, Karin, Seraylan Ormachea, Silvia, Yarleque, Armando, Bonilla, César, Chávez-Olórtegui, Carlos
• Formato: artículo
• Fecha de Publicación: 2012
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: UNMSM-Tesis
• Lenguaje: inglés
• OAI Identifier: oai:cybertesis.unmsm.edu.pe:20.500.12672/27429
• Enlace del recurso: https://hdl.handle.net/20.500.12672/27429; https://doi.org/10.1016/j.toxicon.2012.06.018.
• Nivel de acceso: acceso abierto
• Materia: Bothrops andianus; Serpiente andina; Veneno; https://purl.org/pe-repo/ocde/ford#1.06.03

Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and lethality. The Peruvian anti-bothropic anti-venom displays consistent cross-reactivity with B. andianus venom, by ELISA and Western Blotting and is also effective in neutralizing the venom's toxic activities.