Diferencial de dióxido de carbono como predictor de mortalidad en sepsis y shock séptico en el servicio de emergencia del Hospital Regional Docente de Trujillo

• Autor: Velásquez García, Gabriela Margarita
• Formato: otro
• Fecha de Publicación: 2019
• Institución: Universidad Nacional de Trujillo
• Repositorio: UNITRU-Tesis
• Lenguaje: español
• OAI Identifier: oai:dspace.unitru.edu.pe:20.500.14414/12906
• Enlace del recurso: https://hdl.handle.net/20.500.14414/12906
• Nivel de acceso: acceso abierto
• Materia: Sepsis; Shock séptico; Saturación venosa central; Diferencial de CO2

Sepsis is a potentially fatal organ dysfunction caused by a dysregulation of the response to a host infection. Septic shock occurs with circulatory and cellular / metabolic dysfunction. Then, the shock state occurs when the circulatory system is not able to satisfy this higher demand with a proportional increase in oxygen transport (DO2). This imbalance DO2 / VO2 determines the tissue deoxy. It has been altered by the maldistribution of blood flow. This is due to an increase in oxygen saturation and reduces the difference between the arteriavenous and the production of an increase in cardiac output to maintain consumption. All this is due to a depression of myocardial function due to the increase in pulmonary vascular resistance, with a progressive evolution that causes multi-organ dysfunction and therefore death. The arteriovenous difference of carbon dioxide (ΔCO2), and the venous blood sea mixture of central venous blood, has been a marker of the ability of the cardiovascular system to eliminate carbon dioxide produced in peripheral tissues.