Contenido de compuestos fenólicos y potencial antioxidante en extractos de Prunus rotunda

• Autores: Freitas Babilonia, Keila Kandi, Gómez Canaquiri, Darcy Marbela
• Formato: tesis de grado
• Fecha de Publicación: 2025
• Institución: Universidad Nacional De La Amazonía Peruana
• Repositorio: UNAPIquitos-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.unapiquitos.edu.pe:20.500.12737/12398
• Enlace del recurso: https://hdl.handle.net/20.500.12737/12398
• Nivel de acceso: acceso abierto
• Materia: Metabolitos secundarios; Prunus rotunda; Actividad antioxidante; https://purl.org/pe-repo/ocde/ford#1.06.03

Objective: To quantify the phenolic compound content and evaluate the antioxidant potential in extracts from the leaves and bark of Prunus rotunda. Methodology: Total phenols, flavonoids, anthocyanins, and catechins in the leaf and bark extracts of P. rotunda were quantified using UV-Visible spectroscopy. Antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, calculating the inhibition percentage at concentrations of 1, 10, and 15 mg/mL. Results: The bark exhibited higher concentrations of total phenols (19118.74 mg/100g), flavonoids (35.596 mg/100g), and anthocyanins (24.604 mg/100g) compared to the leaves (13153.05 mg/100g, 25.680 mg/100g, and 19.819 mg/100g, respectively). However, the leaves showed a slightly higher content of catechins (0.073 mg/100g vs. 0.066 mg/100g in the bark). In terms of antioxidant activity, the bark displayed a higher inhibition percentage at lower concentrations, achieving an IC50=0.54 mg/mL, while the leaves only reached comparable inhibition levels at higher concentrations, with an IC50=8.17 mg/mL. Conclusion: The bark of P. rotunda stands out as a rich source of phenolic compounds with remarkable antioxidant activity.