Actividad inhibitoria in vitro de 8 extractos de especies vegetales amazónicas sobre la ?-glucosidasa, Loreto-Iquitos, 2016

• Autor: Vasquez Torres, Diego
• Formato: tesis de grado
• Fecha de Publicación: 2018
• Institución: Universidad Nacional De La Amazonía Peruana
• Repositorio: UNAPIquitos-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.unapiquitos.edu.pe:20.500.12737/7941
• Enlace del recurso: https://hdl.handle.net/20.500.12737/7941
• Nivel de acceso: acceso abierto
• Materia: Extractos vegetales; Potencial de acción; Patología; Hipoglucemiantes; Ensayo; https://purl.org/pe-repo/ocde/ford#3.01.05

In the Peruvian Amazon, traditional knowledge of the antidiabetic effect of native plant species is widely studied by ethnobotanists. In such a way that the objective of this study was to evaluate the extracts of eight plant species as potential inhibitors of the enzyme ?-glucosidase. The samples were processed using standard techniques to obtain the lyophilized aqueous extract. The ?-glucosidase enzyme inhibition assay was developed according to the method proposed by Artanti et al. Year and Srianta et al Year. The species Coussapoa asperifolia "Renaco caspi" showed the highest percentage of inhibition 97% ± 1.12 and an IC50 of 32.1 ?g / mL. Likewise, the species Remijia pedunculata "Chullachaqui caspi", Bahuinia glabra "Pata de vaca", Handroanthus obscurus "Tahuari negro" and Calycophyllum spruceanum "Capirona" reported values that are within the optimal range of antihyperglycemic activity in an in vitro model. In conclusion, several of the species studied could be classified as potential antihyperglycemic agents. Being Coussapoa asperifolia "Renaco caspi", a species with great potential in antihyperglycemic use, due to the results obtained.