Anti-NMDAR Encephalitis: Case report with a long – term follow-up

• Autores: Vences, Miguel A., Saquisela, Víctor V., Barreto-Acevedo, Elliot, Zuñiga, Marco A.
• Formato: artículo
• Fecha de Publicación: 2020
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: Revistas - Universidad Peruana Cayetano Heredia
• Lenguaje: español
• OAI Identifier: oai:revistas.upch.edu.pe:article/3753
• Enlace del recurso: https://revistas.upch.edu.pe/index.php/RNP/article/view/3753
• Nivel de acceso: acceso abierto
• Materia: Encephalitis; N-Methylaspartate ; treatment outcome; Encefalitis; N-Metilaspartato; resultado del tratamiento

Autoimmune encephalitis due to surface antineural antibodies covers a wide spectrum of clinical entities. Encephalitis due to antibodies against the surface antigen of the external portion of the N-methyl-D-aspartate receptor (RNMDA) is the most frequent and best characterized. The case of an adolescent with a clinical picture of neurosychiatric disorder and epileptic seizures of recent onset is presented: he had a positive response for anti-RNMDA antibodies, and a partial response to treatment with corticosteroid therapy and immunoglobulin; therefore, he received additional management with plasma exchange followed by maintenance therapy with immunoglobulin cycles, without the use of immunosuppressants. The results of a long-term follow-up are reported.