Candidemia and antifungal susceptibility in Peruvian hospitals

• Autores: Rios Blanco, Romina, Olsen-Verme, Marcello, Palomino Escalante, Fiorella, Regal Ludowieg, Michelle, Jacobs, Jan, Krapp Lopez, Fiorella, Bustamante Rufino, Beatriz, García Apac, Coralith
• Formato: artículo
• Fecha de Publicación: 2025
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: Revistas - Universidad Peruana Cayetano Heredia
• Lenguaje: español
• OAI Identifier: oai:revistas.upch.edu.pe:article/6233
• Enlace del recurso: https://revistas.upch.edu.pe/index.php/RMH/article/view/6233
• Nivel de acceso: acceso abierto
• Materia: Antifungal agents; Candida; Candidemia; Antifungal Drug Resistance; Antifúngicos; Cándida; Farmacorresistencia Fúngica

Worldwide, Candida bloodstream infections have presented an increase in non-albicans Candida species and resistance to antifungal agents. Objective: To describe the microbiological characteristics of consecutive Candida blood culture isolates. Methods: This study analyzed 73 consecutive Candida blood isolates recovered between July 2017 and July 2019 from routine patient care at 15 Peruvian hospitals, assessing susceptibility to four antifungal agents. Results: The species most frequently detected were Candida parapsilosis 39 (53.4%), Candida albicans 23 (31.5%), and Candida tropicalis 5 (6.8%). Conclusions: All isolates were susceptible to amphotericin B, fluconazole, voriconazole, and anidulafungin. There is a predominance of non-albicans Candida cases in Peru and a high susceptibility to current antifungal drugs.