Updated review of treatment guidelines for schizophrenia in a specialized institute: focus on pharmacological and psychosocial therapies

• Autores: Revilla-Zúñiga, Joshep, Sagástegui-Soto, Abel, Carazas-Vera, María, Saavedra-Castillo, Alfredo
• Formato: artículo
• Fecha de Publicación: 2025
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: Revistas - Universidad Peruana Cayetano Heredia
• Lenguaje: español
• OAI Identifier: oai:revistas.upch.edu.pe:article/6248
• Enlace del recurso: https://revistas.upch.edu.pe/index.php/RNP/article/view/6248
• Nivel de acceso: acceso abierto
• Materia: schizophrenic disorders; paranoid psychoses; health care levels; health services; best practices; trastornos esquizofrénicos; psicosis paranoides; niveles de atención de salud; servicios de salud; mejores prácticas

Schizophrenia is a complex and heterogeneous mental disorder. This article presents an updated review of the main pharmacological and psychosocial recommendations for the management of adult patients withschizophrenia in a level III-2 healthcare facility in Peru. Non-systematic review of the literature recorded on PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library, ScienceDirect, and Google Scholar. The management of schizophrenia in adults requires a pharmacological approach with antipsychotics, which can be administered through oral, rapid-acting or long-acting parenteral routes. Before starting and during the treatment, periodic baseline examinations are recommended. The use of scales also allows the evaluation of antipsychotic response. Regular assessment of adverse/secondary events, such as extrapyramidal symptoms, is recommended. In treatment-resistant schizophrenia, the use of clozapine is recommended. From the psychotherapeutic perspective, individual and group cognitive-behavioural therapy approaches stand out. The clinical management of schizophrenia involves an individualized pharmacological modality, and a non-pharmacological approach that involves both the patient and his/her social context.