Pathological features determinants in the evolution of breast cancer

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Of the various objective factors that have been evaluated and could be used to predict a particular case that has just been treated surgically , has been considered : the size of the primary tumor nodule , the presence or absence of nodal metastases , type of neoplasia , degree of cell differentiati...

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Detalles Bibliográficos
Autores: Rivas Gonzáles, Mauro, Campos Rey de Castro, Jorge
Formato: artículo
Fecha de Publicación:1967
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/5290
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5290
Nivel de acceso:acceso abierto
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dc.title.none.fl_str_mv Pathological features determinants in the evolution of breast cancer
Características anatomopatológicas determinantes en la evolución del cáncer de mama
title Pathological features determinants in the evolution of breast cancer
spellingShingle Pathological features determinants in the evolution of breast cancer
Rivas Gonzáles, Mauro
title_short Pathological features determinants in the evolution of breast cancer
title_full Pathological features determinants in the evolution of breast cancer
title_fullStr Pathological features determinants in the evolution of breast cancer
title_full_unstemmed Pathological features determinants in the evolution of breast cancer
title_sort Pathological features determinants in the evolution of breast cancer
dc.creator.none.fl_str_mv Rivas Gonzáles, Mauro
Campos Rey de Castro, Jorge
author Rivas Gonzáles, Mauro
author_facet Rivas Gonzáles, Mauro
Campos Rey de Castro, Jorge
author_role author
author2 Campos Rey de Castro, Jorge
author2_role author
description Of the various objective factors that have been evaluated and could be used to predict a particular case that has just been treated surgically , has been considered : the size of the primary tumor nodule , the presence or absence of nodal metastases , type of neoplasia , degree of cell differentiation, degree of lymphoplasmacytic infiltration and fibrosis. From the above elements we found that the degree of fibrosis and the degree of cell differentiation does not appear to be useful because no significant differences between the group of patients alive and dead by the group of neoplasia. In other words, these factors do not appear to influence the course of the disease . Instead, the following factors: primary tumor size , degree of lymphoplasmacytic infiltration of the tumor and lymph node metastasis is if valuable elements in the prediction of evolution. In short, one could argue that the smaller is the primary tumor nodule has no axillary metastases and marked lymphoplasmacytic reaction exists in the primary tumor, the prognosis of the case will be favorable. Conversely, the larger the primary tumor, axillary metastases and there is little or no reaction linfoplasmocitaria the primary tumor , the chances of survival are restricted. The considerations just made in the previous paragraph refer to cases treated with the same procedure , at the time it was made (1952-1953) , was considered the treatment of choice for breast cancer (radical mastectomy ) ; currently no reason to think that the treatment of breast cancer that has extended to the internal mammary chain ( ultra-radical mastectomy ) , the validity of the above previous paragraphs no longer take place.
publishDate 1967
dc.date.none.fl_str_mv 1967-03-13
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5290
10.15381/anales.v50i1.5290
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5290
identifier_str_mv 10.15381/anales.v50i1.5290
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5290/4365
dc.rights.none.fl_str_mv Derechos de autor 1967 Mauro Rivas Gonzáles, Jorge Campos Rey de Castro
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 1967 Mauro Rivas Gonzáles, Jorge Campos Rey de Castro
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 50 No. 1 (1967); 1-24
Anales de la Facultad de Medicina; Vol. 50 Núm. 1 (1967); 1-24
1609-9419
1025-5583
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spelling Pathological features determinants in the evolution of breast cancerCaracterísticas anatomopatológicas determinantes en la evolución del cáncer de mamaRivas Gonzáles, MauroCampos Rey de Castro, JorgeOf the various objective factors that have been evaluated and could be used to predict a particular case that has just been treated surgically , has been considered : the size of the primary tumor nodule , the presence or absence of nodal metastases , type of neoplasia , degree of cell differentiation, degree of lymphoplasmacytic infiltration and fibrosis. From the above elements we found that the degree of fibrosis and the degree of cell differentiation does not appear to be useful because no significant differences between the group of patients alive and dead by the group of neoplasia. In other words, these factors do not appear to influence the course of the disease . Instead, the following factors: primary tumor size , degree of lymphoplasmacytic infiltration of the tumor and lymph node metastasis is if valuable elements in the prediction of evolution. In short, one could argue that the smaller is the primary tumor nodule has no axillary metastases and marked lymphoplasmacytic reaction exists in the primary tumor, the prognosis of the case will be favorable. Conversely, the larger the primary tumor, axillary metastases and there is little or no reaction linfoplasmocitaria the primary tumor , the chances of survival are restricted. The considerations just made in the previous paragraph refer to cases treated with the same procedure , at the time it was made (1952-1953) , was considered the treatment of choice for breast cancer (radical mastectomy ) ; currently no reason to think that the treatment of breast cancer that has extended to the internal mammary chain ( ultra-radical mastectomy ) , the validity of the above previous paragraphs no longer take place.De los diferentes elementos objetivos que se han evaluado y que podrían ser usados para predecir un determinado caso que acaba de ser tratado quirúrgicamente, se ha considerado: el tamaño del nódulo tumoral primario, la presencia o no de metástasis ganglionar, el tipo de la neoplasia, grado de diferenciación celular, grado de infiltración linfoplasmocitaria y de fibrosis. De los elementos anteriormente citados hemos encontrado que, el grado de fibrosis y el grado de diferenciación celular no parecen ser útiles porque no presentan diferencias significativas entre el grupo de pacientes vivos y el grupo de muertos por la neoplasia. En otras palabras, estos factores no parecen influir en la evolución de la enfermedad. En cambio, los siguientes factores: tamaño del tumor primario, el grado de infiltración linfoplasmocitaria del tumor y la presencia de metástasis ganglionar si constituye elementos valiosos en la predicción de la evolución. Resumiendo, se podría afirmar que entre más pequeño sea el nódulo tumoral primario, haya ausencia de metástasis axilar y exista acentuada reacción linfoplasmocitaria en el tumor primario, el pronóstico del caso será favorable. Al revés, cuanto más grande sea el tumor primario, exista metástasis axilar y una escasa o ausencia de reacción linfoplasmocitaria en el tumor primario, las posibilidades de sobrevida son restringidas. Las consideraciones que se acaban de hacer en el párrafo anterior se refieren a casos tratados con el mismo procedimiento que, en la época en que éste fue realizado (1952-1953), era considerado el tratamiento de elección para el cáncer de mama (mastectomía radical); no hay motivo para pensar actualmente en que el tratamiento del cáncer de mama que se ha ampliado a la cadena mamaria interna (mastectomia ultraradical), la vigencia de lo expuesto en párrafos anteriores haya dejado de tener lugar.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana1967-03-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/529010.15381/anales.v50i1.5290Anales de la Facultad de Medicina; Vol. 50 No. 1 (1967); 1-24Anales de la Facultad de Medicina; Vol. 50 Núm. 1 (1967); 1-241609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5290/4365Derechos de autor 1967 Mauro Rivas Gonzáles, Jorge Campos Rey de Castrohttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/52902020-04-11T19:03:43Z
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