Drug interaction in Geriatrics

• Autor: OSCANOA, TEODORO
• Formato: artículo
• Fecha de Publicación: 2004
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/1403
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1403
• Nivel de acceso: acceso abierto
• Materia: Interacciones de drogas; anciano; envejecimiento; monitoreo de drogas; sistemas de registro de reacción adversa a medicamentos; geriatría; Drug interactions; aged; aging; drug monitoring; adverse drug reaction reporting system; geriatrics

Elderly patients have three main characteristics that differentiate them from other population groups: polypathology, polypharmacy and physiologic changes related with aging that alter drugs’ pharmocokinetic and pharmacodynamic. These three factors increase drug-drug interactions (DDI) in frequency and severity. Drug-drug interactions are part of drug related problems (DRP) in elderly patient that need to be studied in regards to its epidemiology and adequate strategies to prevent it. Prudent use of medications and vigilant drug monitoring are essential to avoid adverse drug reactions caused by drug-drug interactions.