Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis.
Descripción del Articulo
The neuroendocrine tumor (NET) is of difficult diagnosis due to nonspecific symptoms; management is also a challenge. We present the case of a 78 year-old male who suffered of chronic upper abdominal pain and was admitted to emergency with intestinal obstruction and symptoms of carcinoid syndrome (C...
| Autores: | , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2015 |
| Institución: | Universidad Nacional Mayor de San Marcos |
| Repositorio: | Revistas - Universidad Nacional Mayor de San Marcos |
| Lenguaje: | español |
| OAI Identifier: | oai:ojs.csi.unmsm:article/11147 |
| Enlace del recurso: | https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11147 |
| Nivel de acceso: | acceso abierto |
| Materia: | Ileal neuroendocrine tumor carcinoid syndrome neuroendocrine tumor. Tumor neuroendocrino ileal síndrome carcinoide tumores neuroendocrinos. |
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Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis.Tumor neuroendocrino ileal con síndrome carcinoide, patología de difícil diagnóstico y pronóstico variable.Miranda, GonzaloLuna, LauraIleal neuroendocrine tumorcarcinoid syndromeneuroendocrine tumor.Tumor neuroendocrino ilealsíndrome carcinoidetumores neuroendocrinos.The neuroendocrine tumor (NET) is of difficult diagnosis due to nonspecific symptoms; management is also a challenge. We present the case of a 78 year-old male who suffered of chronic upper abdominal pain and was admitted to emergency with intestinal obstruction and symptoms of carcinoid syndrome (CS). At surgery an ileal tumor was resected with pathology report of NET positive for chromogranin A and ki 67 proliferative index of 2-3%. The patient continued with CS symptoms and presented high levels of 5-HIAA and liver metastases by MRI. Octreotide was started with good outcome. Experience with this case indicates to be alert at symptoms of functioning NET, due to an increase in its incidence. It is useful to request immunohistochemical markers. Identification of NET with low grade mitosis and proliferation signal good prognosis.Los tumores neuroendocrinos (TNE) presentan dificultad en el diagnóstico por sus síntomas inespecíficos y el manejo es un reto. Se presenta el caso de un varón de 78 años de edad, con dolor crónico en hemiabdomen superior. Ingresó a emergencia con obstrucción intestinal y síntomas de síndrome carcinoide (SC). En cirugía se resecó tumor ileal con resultado anatomopatológico de tumor neuroendocrino, cromogranina positivo, índice proliferativo ki 67 de 2 a 3%. El paciente continuó con síntomas de SC, altos niveles de 5-HIA, metástasis hepáticas en RMN. Se inició octreotide con adecuada respuesta clínica. La experiencia con el presente caso indica estar alerta con los síntomas de TNE funcionantes, debido al aumento en su incidencia. Es de utilidad solicitar marcadores inmunohistoquimicos. La identificación de un TNE con índice de mitosis y proliferación bajo indica buen pronóstico.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana2015-06-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1114710.15381/anales.v76i2.11147Anales de la Facultad de Medicina; Vol. 76 No. 2 (2015); 193-197Anales de la Facultad de Medicina; Vol. 76 Núm. 2 (2015); 193-1971609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11147/10093Derechos de autor 2015 Gonzalo Miranda, Laura Lunahttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/111472020-04-16T21:56:49Z |
| dc.title.none.fl_str_mv |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. Tumor neuroendocrino ileal con síndrome carcinoide, patología de difícil diagnóstico y pronóstico variable. |
| title |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. |
| spellingShingle |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. Miranda, Gonzalo Ileal neuroendocrine tumor carcinoid syndrome neuroendocrine tumor. Tumor neuroendocrino ileal síndrome carcinoide tumores neuroendocrinos. |
| title_short |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. |
| title_full |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. |
| title_fullStr |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. |
| title_full_unstemmed |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. |
| title_sort |
Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis. |
| dc.creator.none.fl_str_mv |
Miranda, Gonzalo Luna, Laura |
| author |
Miranda, Gonzalo |
| author_facet |
Miranda, Gonzalo Luna, Laura |
| author_role |
author |
| author2 |
Luna, Laura |
| author2_role |
author |
| dc.subject.none.fl_str_mv |
Ileal neuroendocrine tumor carcinoid syndrome neuroendocrine tumor. Tumor neuroendocrino ileal síndrome carcinoide tumores neuroendocrinos. |
| topic |
Ileal neuroendocrine tumor carcinoid syndrome neuroendocrine tumor. Tumor neuroendocrino ileal síndrome carcinoide tumores neuroendocrinos. |
| description |
The neuroendocrine tumor (NET) is of difficult diagnosis due to nonspecific symptoms; management is also a challenge. We present the case of a 78 year-old male who suffered of chronic upper abdominal pain and was admitted to emergency with intestinal obstruction and symptoms of carcinoid syndrome (CS). At surgery an ileal tumor was resected with pathology report of NET positive for chromogranin A and ki 67 proliferative index of 2-3%. The patient continued with CS symptoms and presented high levels of 5-HIAA and liver metastases by MRI. Octreotide was started with good outcome. Experience with this case indicates to be alert at symptoms of functioning NET, due to an increase in its incidence. It is useful to request immunohistochemical markers. Identification of NET with low grade mitosis and proliferation signal good prognosis. |
| publishDate |
2015 |
| dc.date.none.fl_str_mv |
2015-06-15 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11147 10.15381/anales.v76i2.11147 |
| url |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11147 |
| identifier_str_mv |
10.15381/anales.v76i2.11147 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11147/10093 |
| dc.rights.none.fl_str_mv |
Derechos de autor 2015 Gonzalo Miranda, Laura Luna https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Derechos de autor 2015 Gonzalo Miranda, Laura Luna https://creativecommons.org/licenses/by-nc-sa/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana |
| publisher.none.fl_str_mv |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana |
| dc.source.none.fl_str_mv |
Anales de la Facultad de Medicina; Vol. 76 No. 2 (2015); 193-197 Anales de la Facultad de Medicina; Vol. 76 Núm. 2 (2015); 193-197 1609-9419 1025-5583 reponame:Revistas - Universidad Nacional Mayor de San Marcos instname:Universidad Nacional Mayor de San Marcos instacron:UNMSM |
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Universidad Nacional Mayor de San Marcos |
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UNMSM |
| institution |
UNMSM |
| reponame_str |
Revistas - Universidad Nacional Mayor de San Marcos |
| collection |
Revistas - Universidad Nacional Mayor de San Marcos |
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Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
