Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study

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Objective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010...

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Detalles Bibliográficos
Autores: Marín-Medina, Daniel S., Castaño-Montoya, Juan P., Carmona-Villada, Hans, Villada-Franco, Vanessa, Duque-Salazar, Catalina, Vélez-Monsalve, José D., Buitrago, Diana P., Rodríguez, Maria C., Montilla, Carlos A., Sánchez-Duque, Jorge A.
Formato: artículo
Fecha de Publicación:2023
Institución:Universidad Nacional Hermilio Valdizan
Repositorio:Revistas - Universidad Nacional Hermilio Valdizán
Lenguaje:español
OAI Identifier:oai:revistas.unheval.edu.pe:article/1830
Enlace del recurso:http://revistas.unheval.edu.pe/index.php/repis/article/view/1830
Nivel de acceso:acceso abierto
Materia:analgesia
bloqueo nervioso
pregabalina
neuralgia
nerve block
pregabalin
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network_acronym_str REVUNHEVAL
network_name_str Revistas - Universidad Nacional Hermilio Valdizán
repository_id_str
dc.title.none.fl_str_mv Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
Terapia con pregabalina versus bloqueos intervencionistas en dolor neuropático: Un estudio de cohorte
title Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
spellingShingle Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
Marín-Medina, Daniel S.
analgesia
bloqueo nervioso
pregabalina
neuralgia
analgesia
nerve block
pregabalin
neuralgia
title_short Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
title_full Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
title_fullStr Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
title_full_unstemmed Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
title_sort Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
dc.creator.none.fl_str_mv Marín-Medina, Daniel S.
Castaño-Montoya, Juan P.
Carmona-Villada, Hans
Villada-Franco, Vanessa
Duque-Salazar, Catalina
Vélez-Monsalve, José D.
Buitrago, Diana P.
Rodríguez, Maria C.
Montilla, Carlos A.
Sánchez-Duque, Jorge A.
author Marín-Medina, Daniel S.
author_facet Marín-Medina, Daniel S.
Castaño-Montoya, Juan P.
Carmona-Villada, Hans
Villada-Franco, Vanessa
Duque-Salazar, Catalina
Vélez-Monsalve, José D.
Buitrago, Diana P.
Rodríguez, Maria C.
Montilla, Carlos A.
Sánchez-Duque, Jorge A.
author_role author
author2 Castaño-Montoya, Juan P.
Carmona-Villada, Hans
Villada-Franco, Vanessa
Duque-Salazar, Catalina
Vélez-Monsalve, José D.
Buitrago, Diana P.
Rodríguez, Maria C.
Montilla, Carlos A.
Sánchez-Duque, Jorge A.
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv analgesia
bloqueo nervioso
pregabalina
neuralgia
analgesia
nerve block
pregabalin
neuralgia
topic analgesia
bloqueo nervioso
pregabalina
neuralgia
analgesia
nerve block
pregabalin
neuralgia
description Objective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010-2016. The outcome was assessed at three months in each cohort and was defined as the change in pain intensity according to the visual analog pain scale. The comparison between cohorts and the effectiveness of the intervention was evaluated through repeated measures analysis with the generalized estimating equation. Results: a total of 1451 patients with pain were selected, of these, only 94 met the inclusion criteria. Sixty-two (66%) patients received a pharmacological scheme with pregabalin, and 32 patients (34%) underwent blockages. The pain intensity prior to pregabalin treatment was 7.3 ± 1.8 and 8.9 ± 1.2 in the group with blocks, p = 0.005. The intensity of posterior pain in the group with pregabalin was 3.5 ± 2.4, with an average improvement of 53.9%, while in the group with blocks, it was 2.5 ± 2 with an average improvement of 70.7%. Interventional management reduces pain 2.09 times more compared to pregabalin therapy (p <0.001). Conclusions: the use of interventional blocks in the treatment of neuropathic pain should be considered in patients with moderate to severe neuropathic pain.
publishDate 2023
dc.date.none.fl_str_mv 2023-12-30
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://revistas.unheval.edu.pe/index.php/repis/article/view/1830
10.35839/repis.7.4.1830
url http://revistas.unheval.edu.pe/index.php/repis/article/view/1830
identifier_str_mv 10.35839/repis.7.4.1830
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1828
http://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1850
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidad Nacional Hermilio Valdizán
publisher.none.fl_str_mv Universidad Nacional Hermilio Valdizán
dc.source.none.fl_str_mv Peruvian Journal of Health Research; Vol. 7 No. 4 (2023); e1830
Revista Peruana de Investigación en Salud; Vol. 7 Núm. 4 (2023); e1830
Revista Peruana de Investigación en Salud; v. 7 n. 4 (2023); e1830
2616-6097
reponame:Revistas - Universidad Nacional Hermilio Valdizán
instname:Universidad Nacional Hermilio Valdizan
instacron:UNHEVAL
instname_str Universidad Nacional Hermilio Valdizan
instacron_str UNHEVAL
institution UNHEVAL
reponame_str Revistas - Universidad Nacional Hermilio Valdizán
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repository.name.fl_str_mv
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spelling Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort studyTerapia con pregabalina versus bloqueos intervencionistas en dolor neuropático: Un estudio de cohorteMarín-Medina, Daniel S.Castaño-Montoya, Juan P.Carmona-Villada, HansVillada-Franco, VanessaDuque-Salazar, CatalinaVélez-Monsalve, José D.Buitrago, Diana P.Rodríguez, Maria C.Montilla, Carlos A.Sánchez-Duque, Jorge A.analgesiabloqueo nerviosopregabalinaneuralgiaanalgesianerve blockpregabalinneuralgiaObjective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010-2016. The outcome was assessed at three months in each cohort and was defined as the change in pain intensity according to the visual analog pain scale. The comparison between cohorts and the effectiveness of the intervention was evaluated through repeated measures analysis with the generalized estimating equation. Results: a total of 1451 patients with pain were selected, of these, only 94 met the inclusion criteria. Sixty-two (66%) patients received a pharmacological scheme with pregabalin, and 32 patients (34%) underwent blockages. The pain intensity prior to pregabalin treatment was 7.3 ± 1.8 and 8.9 ± 1.2 in the group with blocks, p = 0.005. The intensity of posterior pain in the group with pregabalin was 3.5 ± 2.4, with an average improvement of 53.9%, while in the group with blocks, it was 2.5 ± 2 with an average improvement of 70.7%. Interventional management reduces pain 2.09 times more compared to pregabalin therapy (p <0.001). Conclusions: the use of interventional blocks in the treatment of neuropathic pain should be considered in patients with moderate to severe neuropathic pain.Objetivo: comparar la disminución en el dolor en pacientes con terapia con pregabalina frente a bloqueos intervencionistas. Materiales y métodos: estudio de cohorte retrospectiva, se reclutó pacientes mayores de 18 años diagnosticados con dolor de tipo neuropático de centro de referencia de la ciudad de Pereira, Colombia, entre los años 2010 a 2016. Se evaluó la variación en la intensidad del dolor. La comparación entre cohortes y la efectividad de la intervención se evaluó a través del análisis de medias repetidas con la ecuación de estimación generalizada. Resultados: se incluyeron 94 pacientes con dolor neuropático. A 62 (66%) pacientes se les formuló un esquema farmacológico con pregabalina y a 32 (34%) pacientes se les realizó bloqueos. La intensidad del dolor previa al tratamiento con pregabalina fue de 7,3 ± 1,8 y de 8,9 ± 1,2 en el grupo con bloqueos, p=0,005. La intensidad del dolor posterior en el grupo con pregabalina fue de 3,5 ± 2,4, con una mejoría media de 53,9%, mientras que en el grupo con bloqueos fue del 2,5 ± 2 con una mejoría media de 70,7%. El manejo intervencionista logró una reducción 2,09 veces mayor comparada con la pregabalina (p<0,001). Conclusiones: el empleo de bloqueos intervencionistas en el tratamiento del dolor neuropático debe ser considerado en pacientes con dolor neuropático moderado a severo.Universidad Nacional Hermilio Valdizán2023-12-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttp://revistas.unheval.edu.pe/index.php/repis/article/view/183010.35839/repis.7.4.1830Peruvian Journal of Health Research; Vol. 7 No. 4 (2023); e1830Revista Peruana de Investigación en Salud; Vol. 7 Núm. 4 (2023); e1830Revista Peruana de Investigación en Salud; v. 7 n. 4 (2023); e18302616-6097reponame:Revistas - Universidad Nacional Hermilio Valdizáninstname:Universidad Nacional Hermilio Valdizaninstacron:UNHEVALspahttp://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1828http://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1850Derechos de autor 2024 Daniel S. Marín-Medina, Juan P. Castaño-Montoya, Hans Carmona-Villada, Vanessa Villada-Franco, Catalina Duque-Salazar, José D. Vélez-Monsalve, Diana P. Buitrago, Maria C. Rodríguez, Carlos A. Montilla, Jorge A. Sánchez-Duquehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:revistas.unheval.edu.pe:article/18302024-02-07T21:53:32Z
score 13.100461
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