Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study
Descripción del Articulo
Objective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010...
Autores: | , , , , , , , , , |
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Formato: | artículo |
Fecha de Publicación: | 2023 |
Institución: | Universidad Nacional Hermilio Valdizan |
Repositorio: | Revistas - Universidad Nacional Hermilio Valdizán |
Lenguaje: | español |
OAI Identifier: | oai:revistas.unheval.edu.pe:article/1830 |
Enlace del recurso: | http://revistas.unheval.edu.pe/index.php/repis/article/view/1830 |
Nivel de acceso: | acceso abierto |
Materia: | analgesia bloqueo nervioso pregabalina neuralgia nerve block pregabalin |
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oai:revistas.unheval.edu.pe:article/1830 |
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REVUNHEVAL |
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Revistas - Universidad Nacional Hermilio Valdizán |
repository_id_str |
|
dc.title.none.fl_str_mv |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study Terapia con pregabalina versus bloqueos intervencionistas en dolor neuropático: Un estudio de cohorte |
title |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study |
spellingShingle |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study Marín-Medina, Daniel S. analgesia bloqueo nervioso pregabalina neuralgia analgesia nerve block pregabalin neuralgia |
title_short |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study |
title_full |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study |
title_fullStr |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study |
title_full_unstemmed |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study |
title_sort |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort study |
dc.creator.none.fl_str_mv |
Marín-Medina, Daniel S. Castaño-Montoya, Juan P. Carmona-Villada, Hans Villada-Franco, Vanessa Duque-Salazar, Catalina Vélez-Monsalve, José D. Buitrago, Diana P. Rodríguez, Maria C. Montilla, Carlos A. Sánchez-Duque, Jorge A. |
author |
Marín-Medina, Daniel S. |
author_facet |
Marín-Medina, Daniel S. Castaño-Montoya, Juan P. Carmona-Villada, Hans Villada-Franco, Vanessa Duque-Salazar, Catalina Vélez-Monsalve, José D. Buitrago, Diana P. Rodríguez, Maria C. Montilla, Carlos A. Sánchez-Duque, Jorge A. |
author_role |
author |
author2 |
Castaño-Montoya, Juan P. Carmona-Villada, Hans Villada-Franco, Vanessa Duque-Salazar, Catalina Vélez-Monsalve, José D. Buitrago, Diana P. Rodríguez, Maria C. Montilla, Carlos A. Sánchez-Duque, Jorge A. |
author2_role |
author author author author author author author author author |
dc.subject.none.fl_str_mv |
analgesia bloqueo nervioso pregabalina neuralgia analgesia nerve block pregabalin neuralgia |
topic |
analgesia bloqueo nervioso pregabalina neuralgia analgesia nerve block pregabalin neuralgia |
description |
Objective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010-2016. The outcome was assessed at three months in each cohort and was defined as the change in pain intensity according to the visual analog pain scale. The comparison between cohorts and the effectiveness of the intervention was evaluated through repeated measures analysis with the generalized estimating equation. Results: a total of 1451 patients with pain were selected, of these, only 94 met the inclusion criteria. Sixty-two (66%) patients received a pharmacological scheme with pregabalin, and 32 patients (34%) underwent blockages. The pain intensity prior to pregabalin treatment was 7.3 ± 1.8 and 8.9 ± 1.2 in the group with blocks, p = 0.005. The intensity of posterior pain in the group with pregabalin was 3.5 ± 2.4, with an average improvement of 53.9%, while in the group with blocks, it was 2.5 ± 2 with an average improvement of 70.7%. Interventional management reduces pain 2.09 times more compared to pregabalin therapy (p <0.001). Conclusions: the use of interventional blocks in the treatment of neuropathic pain should be considered in patients with moderate to severe neuropathic pain. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-12-30 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://revistas.unheval.edu.pe/index.php/repis/article/view/1830 10.35839/repis.7.4.1830 |
url |
http://revistas.unheval.edu.pe/index.php/repis/article/view/1830 |
identifier_str_mv |
10.35839/repis.7.4.1830 |
dc.language.none.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
http://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1828 http://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1850 |
dc.rights.none.fl_str_mv |
http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html |
dc.publisher.none.fl_str_mv |
Universidad Nacional Hermilio Valdizán |
publisher.none.fl_str_mv |
Universidad Nacional Hermilio Valdizán |
dc.source.none.fl_str_mv |
Peruvian Journal of Health Research; Vol. 7 No. 4 (2023); e1830 Revista Peruana de Investigación en Salud; Vol. 7 Núm. 4 (2023); e1830 Revista Peruana de Investigación en Salud; v. 7 n. 4 (2023); e1830 2616-6097 reponame:Revistas - Universidad Nacional Hermilio Valdizán instname:Universidad Nacional Hermilio Valdizan instacron:UNHEVAL |
instname_str |
Universidad Nacional Hermilio Valdizan |
instacron_str |
UNHEVAL |
institution |
UNHEVAL |
reponame_str |
Revistas - Universidad Nacional Hermilio Valdizán |
collection |
Revistas - Universidad Nacional Hermilio Valdizán |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
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1844434259076448256 |
spelling |
Pregabalin therapy versus interventional blocks in neuropathic pain: A cohort studyTerapia con pregabalina versus bloqueos intervencionistas en dolor neuropático: Un estudio de cohorteMarín-Medina, Daniel S.Castaño-Montoya, Juan P.Carmona-Villada, HansVillada-Franco, VanessaDuque-Salazar, CatalinaVélez-Monsalve, José D.Buitrago, Diana P.Rodríguez, Maria C.Montilla, Carlos A.Sánchez-Duque, Jorge A.analgesiabloqueo nerviosopregabalinaneuralgiaanalgesianerve blockpregabalinneuralgiaObjective: tcompare the decrease in pain in patients with pregabalin therapy versus interventional blocks. Materials and methods: retrospective cohort study that included patients older than 18 years diagnosed with neuropathic pain from a reference center in Pereira, Colombia, between the years 2010-2016. The outcome was assessed at three months in each cohort and was defined as the change in pain intensity according to the visual analog pain scale. The comparison between cohorts and the effectiveness of the intervention was evaluated through repeated measures analysis with the generalized estimating equation. Results: a total of 1451 patients with pain were selected, of these, only 94 met the inclusion criteria. Sixty-two (66%) patients received a pharmacological scheme with pregabalin, and 32 patients (34%) underwent blockages. The pain intensity prior to pregabalin treatment was 7.3 ± 1.8 and 8.9 ± 1.2 in the group with blocks, p = 0.005. The intensity of posterior pain in the group with pregabalin was 3.5 ± 2.4, with an average improvement of 53.9%, while in the group with blocks, it was 2.5 ± 2 with an average improvement of 70.7%. Interventional management reduces pain 2.09 times more compared to pregabalin therapy (p <0.001). Conclusions: the use of interventional blocks in the treatment of neuropathic pain should be considered in patients with moderate to severe neuropathic pain.Objetivo: comparar la disminución en el dolor en pacientes con terapia con pregabalina frente a bloqueos intervencionistas. Materiales y métodos: estudio de cohorte retrospectiva, se reclutó pacientes mayores de 18 años diagnosticados con dolor de tipo neuropático de centro de referencia de la ciudad de Pereira, Colombia, entre los años 2010 a 2016. Se evaluó la variación en la intensidad del dolor. La comparación entre cohortes y la efectividad de la intervención se evaluó a través del análisis de medias repetidas con la ecuación de estimación generalizada. Resultados: se incluyeron 94 pacientes con dolor neuropático. A 62 (66%) pacientes se les formuló un esquema farmacológico con pregabalina y a 32 (34%) pacientes se les realizó bloqueos. La intensidad del dolor previa al tratamiento con pregabalina fue de 7,3 ± 1,8 y de 8,9 ± 1,2 en el grupo con bloqueos, p=0,005. La intensidad del dolor posterior en el grupo con pregabalina fue de 3,5 ± 2,4, con una mejoría media de 53,9%, mientras que en el grupo con bloqueos fue del 2,5 ± 2 con una mejoría media de 70,7%. El manejo intervencionista logró una reducción 2,09 veces mayor comparada con la pregabalina (p<0,001). Conclusiones: el empleo de bloqueos intervencionistas en el tratamiento del dolor neuropático debe ser considerado en pacientes con dolor neuropático moderado a severo.Universidad Nacional Hermilio Valdizán2023-12-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttp://revistas.unheval.edu.pe/index.php/repis/article/view/183010.35839/repis.7.4.1830Peruvian Journal of Health Research; Vol. 7 No. 4 (2023); e1830Revista Peruana de Investigación en Salud; Vol. 7 Núm. 4 (2023); e1830Revista Peruana de Investigación en Salud; v. 7 n. 4 (2023); e18302616-6097reponame:Revistas - Universidad Nacional Hermilio Valdizáninstname:Universidad Nacional Hermilio Valdizaninstacron:UNHEVALspahttp://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1828http://revistas.unheval.edu.pe/index.php/repis/article/view/1830/1850Derechos de autor 2024 Daniel S. Marín-Medina, Juan P. Castaño-Montoya, Hans Carmona-Villada, Vanessa Villada-Franco, Catalina Duque-Salazar, José D. Vélez-Monsalve, Diana P. Buitrago, Maria C. Rodríguez, Carlos A. Montilla, Jorge A. Sánchez-Duquehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:revistas.unheval.edu.pe:article/18302024-02-07T21:53:32Z |
score |
13.102717 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).