Early- and late -onset preeclampsia: an old disease, new ideas

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Significant differences between preeclampsia manifestations before (early-onset) and after 34weeks (late-onset) raise the possibility that these are two different diseases. This hypothesisis strengthened based on genetic, epidemiological and placental differences. However, recentstudies show the pos...

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Detalles Bibliográficos
Autores: Lacunza Paredes, Rommel Omar, Pacheco Romero, José
Formato: artículo
Fecha de Publicación:2015
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Lenguaje:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/159
Enlace del recurso:http://51.222.106.123/index.php/RPGO/article/view/159
Nivel de acceso:acceso abierto
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spelling Early- and late -onset preeclampsia: an old disease, new ideasPreeclampsia de inicio temprano y tar dío: una antigua enfermedad, nuevas ideasLacunza Paredes, Rommel OmarPacheco Romero, JoséSignificant differences between preeclampsia manifestations before (early-onset) and after 34weeks (late-onset) raise the possibility that these are two different diseases. This hypothesisis strengthened based on genetic, epidemiological and placental differences. However, recentstudies show the possibility of temporal continuity between both clinical phenotypes. In thiscontext antiangiogenic phenomena and their relation with the fetus may be crucial in clarifyingthis unanswered question.Keywords: Early-onset preeclampsia, late-onset preeclampsia, antiangiogenic imbalanceLas importantes diferencias que existen entre las manifestaciones de la preeclampsia, antes(inicio temprano) y después de la semana 34 (inicio tardío), plantean la posibilidad quese trate de dos enfermedades distintas. Basada en diferencias genéticas, epidemiológicasy placentarias, esta hipótesis cobra fuerza. Sin embargo, recientes estudios nos muestranla posibilidad de una continuidad clínico temporal entre ambos fenotipos. En este contextolos fenómenos antiangiogénicos y su relación con el feto podrían ser determinantes paraesclarecer la interrogante.Palabras clave: Preeclampsia de inicio temprano, preeclampsia de inicio tardío, desbalanceantiangiogénico.Sociedad Peruana de Obstetricia y Ginecología2015-01-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://51.222.106.123/index.php/RPGO/article/view/159The Peruvian Journal of Gynecology and Obstetrics ; Vol. 60 No. 4 (2014); 351-361Revista Peruana de Ginecología y Obstetricia; Vol. 60 Núm. 4 (2014); 351-3612304-51322304-5124reponame:Revista Peruana de Ginecología y Obstetriciainstname:Sociedad Peruana de Obstetricia y Ginecologíainstacron:SPOGspahttp://51.222.106.123/index.php/RPGO/article/view/159/141info:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/1592015-01-28T22:24:38Z
dc.title.none.fl_str_mv Early- and late -onset preeclampsia: an old disease, new ideas
Preeclampsia de inicio temprano y tar dío: una antigua enfermedad, nuevas ideas
title Early- and late -onset preeclampsia: an old disease, new ideas
spellingShingle Early- and late -onset preeclampsia: an old disease, new ideas
Lacunza Paredes, Rommel Omar
title_short Early- and late -onset preeclampsia: an old disease, new ideas
title_full Early- and late -onset preeclampsia: an old disease, new ideas
title_fullStr Early- and late -onset preeclampsia: an old disease, new ideas
title_full_unstemmed Early- and late -onset preeclampsia: an old disease, new ideas
title_sort Early- and late -onset preeclampsia: an old disease, new ideas
dc.creator.none.fl_str_mv Lacunza Paredes, Rommel Omar
Pacheco Romero, José
author Lacunza Paredes, Rommel Omar
author_facet Lacunza Paredes, Rommel Omar
Pacheco Romero, José
author_role author
author2 Pacheco Romero, José
author2_role author
description Significant differences between preeclampsia manifestations before (early-onset) and after 34weeks (late-onset) raise the possibility that these are two different diseases. This hypothesisis strengthened based on genetic, epidemiological and placental differences. However, recentstudies show the possibility of temporal continuity between both clinical phenotypes. In thiscontext antiangiogenic phenomena and their relation with the fetus may be crucial in clarifyingthis unanswered question.Keywords: Early-onset preeclampsia, late-onset preeclampsia, antiangiogenic imbalance
publishDate 2015
dc.date.none.fl_str_mv 2015-01-28
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://51.222.106.123/index.php/RPGO/article/view/159
url http://51.222.106.123/index.php/RPGO/article/view/159
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://51.222.106.123/index.php/RPGO/article/view/159/141
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
dc.source.none.fl_str_mv The Peruvian Journal of Gynecology and Obstetrics ; Vol. 60 No. 4 (2014); 351-361
Revista Peruana de Ginecología y Obstetricia; Vol. 60 Núm. 4 (2014); 351-361
2304-5132
2304-5124
reponame:Revista Peruana de Ginecología y Obstetricia
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instacron:SPOG
instname_str Sociedad Peruana de Obstetricia y Ginecología
instacron_str SPOG
institution SPOG
reponame_str Revista Peruana de Ginecología y Obstetricia
collection Revista Peruana de Ginecología y Obstetricia
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Early- and late -onset preeclampsia: an old disease, new ideas
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