The natural history of cervical cancer and its behavior from the point of view anatomicopathological

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We have studied the pathways and metastases in 56 autopsies of patients who died from cervical cancer. The extension by continuity is the most common mode of transmission of this neoplasm. Parametria were invaded in 96.4 percent of cases; then follow in order of frequency, the vesico-vaginal septum...

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Autores: Campos Rey de Castro, Jorge, Gonzáles del Riego, Manuel
Formato: artículo
Fecha de Publicación:2015
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Lenguaje:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/1136
Enlace del recurso:http://51.222.106.123/index.php/RPGO/article/view/1136
Nivel de acceso:acceso abierto
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dc.title.none.fl_str_mv The natural history of cervical cancer and its behavior from the point of view anatomicopathological
La historia natural del cáncer del cuello uterino y su comportamiento desde el punto de vista anatomo-patológico
title The natural history of cervical cancer and its behavior from the point of view anatomicopathological
spellingShingle The natural history of cervical cancer and its behavior from the point of view anatomicopathological
Campos Rey de Castro, Jorge
title_short The natural history of cervical cancer and its behavior from the point of view anatomicopathological
title_full The natural history of cervical cancer and its behavior from the point of view anatomicopathological
title_fullStr The natural history of cervical cancer and its behavior from the point of view anatomicopathological
title_full_unstemmed The natural history of cervical cancer and its behavior from the point of view anatomicopathological
title_sort The natural history of cervical cancer and its behavior from the point of view anatomicopathological
dc.creator.none.fl_str_mv Campos Rey de Castro, Jorge
Gonzáles del Riego, Manuel
author Campos Rey de Castro, Jorge
author_facet Campos Rey de Castro, Jorge
Gonzáles del Riego, Manuel
author_role author
author2 Gonzáles del Riego, Manuel
author2_role author
description We have studied the pathways and metastases in 56 autopsies of patients who died from cervical cancer. The extension by continuity is the most common mode of transmission of this neoplasm. Parametria were invaded in 96.4 percent of cases; then follow in order of frequency, the vesico-vaginal septum (69.7 percent), the vagina and the bladder (59 percent), the rectovaginal septum (53 percent), rectum (34 percent), uterine body and annexes (23 percent). Metastasis via the lymphatic system were found in 83.9 percent of patients, being more frequent metastases in pelvic lymph and then in descending order, metastasis was found in lymph lumbar retro-peritoneal (50 percent), mesenteric and mediastinal (18 and 16 percent respectively) and supraclavicular (5.3 percent). .5 In 42 percent of cases caused by blood metastasis was found, with the lungs (20 percent) and liver (16 percent) the most frequently involved organs. In 18 percent of the sick in which hematogenous metastases was found not extrapelvianos lymph node metastasis was found, The most frequent causes of death were: uremia (42.5 percent) and carcinomatosis (34 percent). In 45 cases (80 percent) compression ureteral found in 39 of them bilateral. As a result in 38 patients (68 percent) hydronephrosis was found; in 29 (52 percent) and bilateral hydronephrosis was 2 sided. In 16 cases (28.5 percent) cervical cancer was located in the pelvis and death determined exclusively urinary complications. It is very likely that sick that constitute this group could have benefited with a pelvic evisceration. That said, in other words, 28.5 percent of the cases seem to indicate that, theoretically, a sick four advanced cervical cancer could benefit from the super-radical surgical treatment.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-29
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dc.publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
dc.source.none.fl_str_mv The Peruvian Journal of Gynecology and Obstetrics ; Vol. 3 No. 2 (1957); 65-80
Revista Peruana de Ginecología y Obstetricia; Vol. 3 Núm. 2 (1957); 65-80
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spelling The natural history of cervical cancer and its behavior from the point of view anatomicopathologicalLa historia natural del cáncer del cuello uterino y su comportamiento desde el punto de vista anatomo-patológicoCampos Rey de Castro, JorgeGonzáles del Riego, ManuelWe have studied the pathways and metastases in 56 autopsies of patients who died from cervical cancer. The extension by continuity is the most common mode of transmission of this neoplasm. Parametria were invaded in 96.4 percent of cases; then follow in order of frequency, the vesico-vaginal septum (69.7 percent), the vagina and the bladder (59 percent), the rectovaginal septum (53 percent), rectum (34 percent), uterine body and annexes (23 percent). Metastasis via the lymphatic system were found in 83.9 percent of patients, being more frequent metastases in pelvic lymph and then in descending order, metastasis was found in lymph lumbar retro-peritoneal (50 percent), mesenteric and mediastinal (18 and 16 percent respectively) and supraclavicular (5.3 percent). .5 In 42 percent of cases caused by blood metastasis was found, with the lungs (20 percent) and liver (16 percent) the most frequently involved organs. In 18 percent of the sick in which hematogenous metastases was found not extrapelvianos lymph node metastasis was found, The most frequent causes of death were: uremia (42.5 percent) and carcinomatosis (34 percent). In 45 cases (80 percent) compression ureteral found in 39 of them bilateral. As a result in 38 patients (68 percent) hydronephrosis was found; in 29 (52 percent) and bilateral hydronephrosis was 2 sided. In 16 cases (28.5 percent) cervical cancer was located in the pelvis and death determined exclusively urinary complications. It is very likely that sick that constitute this group could have benefited with a pelvic evisceration. That said, in other words, 28.5 percent of the cases seem to indicate that, theoretically, a sick four advanced cervical cancer could benefit from the super-radical surgical treatment.Se ha estudiado las vías de propagación y metástasis en 56 autopsias de pacientes que murieron por cáncer del cérvix. La extensión por continuidad es la vía de propagación más frecuente de esta neoplasia. Los parametrios estuvieron invadidos en el 96.4 por ciento de los casos; luego siguen en orden de frecuencia el tabique vésico-vaginal (69.7 por ciento), la vagina y la vejiga (59 por ciento), el tabique recto-vaginal (53 por ciento), el recto (34 por ciento), el cuerpo uterino y los anexos (23 por ciento). Metástasis por vía linfática fueron encontradas en el 83.9 por ciento de las pacientes, siendo más frecuentes las metástasis en ganglios pelvianos y luego en orden decreciente, se encontró metástasis en ganglios lumbares retro-peritoneales (50 por ciento), mesentéricos y mediastinales (18 y 16 por ciento respectivamente) y supraclaviculares (5.3 por ciento). En el 42 .5 por ciento de los casos se encontró metástasis producidas por vía sanguínea, siendo los pulmones (20 por ciento) y el hígado (16 por ciento) los órganos comprometidos con mayor frecuencia. En el 18 por ciento de las enfermas en las que se encontró metástasis hematógenas, no se encontró metástasis en ganglios linfáticos extrapelvianos, Las causas de muerte más frecuentes fueron: uremia (42.5 por ciento) y carcinomatosis (34 por ciento). En 45 casos (80 por ciento) se encontró compresión ureteral, en 39 de ellos bilateral. Como consecuencia de ello en 38 pacientes (68 por ciento) se encontró hidronefrosis; en 29 (52 por ciento) la hidronefrosis fue bilateral y en 2 unilateral. En 16 casos (28.5 por ciento) el cáncer cervical estuvo localizado dentro de la pelvis y determinó la muerte por complicaciones exclusivamente urinarias. Es muy probable que las enfermas que constituyen este grupo podrían haberse beneficiado con una evisceración pelviana. Dicho esto en otras palabras, este 28.5 por ciento de casos parecería indicar que, teóricamente, una enferma de cada cuatro con cáncer cervical avanzado se podría beneficiar con el tratamiento quirúrgico super-radical.Sociedad Peruana de Obstetricia y Ginecología2015-06-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://51.222.106.123/index.php/RPGO/article/view/1136The Peruvian Journal of Gynecology and Obstetrics ; Vol. 3 No. 2 (1957); 65-80Revista Peruana de Ginecología y Obstetricia; Vol. 3 Núm. 2 (1957); 65-802304-51322304-5124reponame:Revista Peruana de Ginecología y Obstetriciainstname:Sociedad Peruana de Obstetricia y Ginecologíainstacron:SPOGspahttp://51.222.106.123/index.php/RPGO/article/view/1136/1091info:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/11362015-07-21T18:05:04Z
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