Overlap syndrome of autoimmune hepatitis and primary biliary cholangitis associated with portal vein thrombosis post COVID-19

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We present the case of a 53-year-old woman with a history of rheumatoid arthritis who, after recovering from a severe COVID-19, developed gastrointestinal bleeding as a manifestation of portal hypertension and progressive liver failure. Based on serology and ultrasound, an overlap syndrome of autoim...

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Detalles Bibliográficos
Autores: Zumaeta Rodríguez, Thalía Isabel, Carrasco Lozano, Luis Enrique, Zamudio Romero, Silvia Patricia, Maya Pérez, Luis Alberto
Formato: artículo
Fecha de Publicación:2021
Institución:Sociedad Peruana de Medicina Interna
Repositorio:Revista de la Sociedad Peruana de Medicina Interna
Lenguaje:español
OAI Identifier:oai:medicinainterna.net.pe:article/636
Enlace del recurso:https://revistamedicinainterna.net/index.php/spmi/article/view/636
Nivel de acceso:acceso abierto
Materia:COVID-19
SARS-CoV-2
hepatitis autoinmune
colangitis biliar primaria
trombosis venosa
vena porta
autoimmune hepatitis
primary biliary cholangitis
venous thrombosis
portal vein
Descripción
Sumario:We present the case of a 53-year-old woman with a history of rheumatoid arthritis who, after recovering from a severe COVID-19, developed gastrointestinal bleeding as a manifestation of portal hypertension and progressive liver failure. Based on serology and ultrasound, an overlap syndrome of autoimmune hepatitis and primary biliary cholangitis associated with portal vein thrombosis were diagnosed. The response to steroids and anticoagulation was favorable. Hepatic involvement, induced by the virus, has been described in COVID-19. However, autoimmune diseases and thromboembolic phenomena can develop, having the liver as a target organ.
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