New therapeutic advances in the management of preeclampsia: A narrative review

• Autores: Tabares-Beltrán, Nicoll Vanessa, Posso-León, Julieth Andrea, Uribe-Romero, Daniel Fernando, Zapata-Loaiza, Yessica, Serna-Trejos, Juan Santiago
• Formato: artículo
• Fecha de Publicación: 2025
• Institución: Sociedad Materno Fetal
• Repositorio: Revista Internacional de Salud Materno Fetal
• Lenguaje: español
• OAI Identifier: oai:ojs2.ojs.revistamaternofetal.com:article/360
• Enlace del recurso: http://ojs.revistamaternofetal.com/index.php/RISMF/article/view/360
• Nivel de acceso: acceso abierto
• Materia: Complicaciones del embarazo; Hipertención inducida por el embarazo; Pre-eclampsia; Tratamientos; Investigación traslacional

Objective: To review emerging therapies targeting the pathophysiology of preeclampsia, including anti-inflammatory approaches, therapies targeting the complement system, anti-angiogenic factors and mesenchymal stem cells. Material and methods: A comprehensive search was performed in databases such as Medline and PubMed, without time restrictions, including research on innovative treatments. Results: Therapies such as statins, complement inhibitors, mesenchymal stem cells and apheresis have demonstrated potential to modulate inflammation, correct angiogenic imbalances and prolong gestation in cases of severe preeclampsia. Conclusion: These therapies offer promising approaches to improve maternal-fetal outcomes. Further multicenter research and interdisciplinary collaborations are essential to validate their efficacy and safety in clinical practice.