Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020

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Objective: determine the complications during the first year after liver transplantation in pediatric patients of the INSN-SB during the period 2016-2020. Materials and methods: Descriptive, cross-sectional study. The medical records of liver transplant patients seen during post-transplant follow-up...

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Autores: Castro-Johanson, Rosa, Tello Quispe, Gabriela, Verastegui S., Rodrigo, Perez Rodriguez, Diana
Formato: artículo
Fecha de Publicación:2024
Institución:Sociedad de Gastroenterología del Perú
Repositorio:Revista de Gastroenterología del Perú
Lenguaje:español
OAI Identifier:oai:ojs.revistagastroperu.com:article/1606
Enlace del recurso:https://revistagastroperu.com/index.php/rgp/article/view/1606
Nivel de acceso:acceso abierto
Materia:Trasplante hepático
Pediatría
Perú
Liver transplantation
Pediatrics
Peru
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dc.title.none.fl_str_mv Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
Complicaciones post trasplante hepático en pacientes pediátricos en un hospital de tercer nivel, Lima-Perú, 2016-2020
title Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
spellingShingle Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
Castro-Johanson, Rosa
Trasplante hepático
Pediatría
Perú
Liver transplantation
Pediatrics
Peru
title_short Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
title_full Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
title_fullStr Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
title_full_unstemmed Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
title_sort Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020
dc.creator.none.fl_str_mv Castro-Johanson, Rosa
Tello Quispe, Gabriela
Verastegui S., Rodrigo
Perez Rodriguez, Diana
author Castro-Johanson, Rosa
author_facet Castro-Johanson, Rosa
Tello Quispe, Gabriela
Verastegui S., Rodrigo
Perez Rodriguez, Diana
author_role author
author2 Tello Quispe, Gabriela
Verastegui S., Rodrigo
Perez Rodriguez, Diana
author2_role author
author
author
dc.subject.none.fl_str_mv Trasplante hepático
Pediatría
Perú
Liver transplantation
Pediatrics
Peru
topic Trasplante hepático
Pediatría
Perú
Liver transplantation
Pediatrics
Peru
description Objective: determine the complications during the first year after liver transplantation in pediatric patients of the INSN-SB during the period 2016-2020. Materials and methods: Descriptive, cross-sectional study. The medical records of liver transplant patients seen during post-transplant follow-up at the INSN-SB were reviewed, collecting epidemiological characteristics, transplant indication; PELD score, CHILD score and complications prior to the transplant, as well as the frequency of the main complications presented during the first year after the transplant. Results: Of the 16 patients evaluated, 62.5% were under 1 year of age, with a median weight of 7.4kg, 50% presented a CHILD C score, with a median PELD of 23, the main reason for transplantation was atresia of bile ducts (62.5%), the main complications prior to transplantation were portal hypertension (75%) and malnutrition (68.8%). All posttransplant patients presented at least one infectious complication: bacterial (53%), CMV infection (75%) and EBV infection (31%); Regarding vascular complications, 25% presented portal vein thrombosis and one patient (6%) presented hepatic artery stenosis; Regarding biliary complications, 12.5% presented biliary fistula, also 12.5% presented bile duct dilation, while 6.25% presented bilioma. Conclusions: Among the main complications of the postliver transplant patient, we can highlight that all patients presented at least one infectious complication (100%), vascular complications in 31% and biliary complications in 31.25% of patients.
publishDate 2024
dc.date.none.fl_str_mv 2024-06-26
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dc.relation.none.fl_str_mv https://revistagastroperu.com/index.php/rgp/article/view/1606/1242
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dc.publisher.none.fl_str_mv Sociedad de Gastroenterología del Perú
publisher.none.fl_str_mv Sociedad de Gastroenterología del Perú
dc.source.none.fl_str_mv Revista de Gastroenterología del Perú; Vol. 44 No. 2 (2024)
Revista de Gastroenterología del Perú; Vol. 44 Núm. 2 (2024)
1609-722X
1022-5129
reponame:Revista de Gastroenterología del Perú
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instacron:SOCIOGASTRO
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reponame_str Revista de Gastroenterología del Perú
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spelling Post liver transplantation complications in pediatric patients in a third level hospital, Lima-Peru, 2016-2020Complicaciones post trasplante hepático en pacientes pediátricos en un hospital de tercer nivel, Lima-Perú, 2016-2020Castro-Johanson, RosaTello Quispe, GabrielaVerastegui S., RodrigoPerez Rodriguez, DianaTrasplante hepáticoPediatríaPerúLiver transplantationPediatricsPeruObjective: determine the complications during the first year after liver transplantation in pediatric patients of the INSN-SB during the period 2016-2020. Materials and methods: Descriptive, cross-sectional study. The medical records of liver transplant patients seen during post-transplant follow-up at the INSN-SB were reviewed, collecting epidemiological characteristics, transplant indication; PELD score, CHILD score and complications prior to the transplant, as well as the frequency of the main complications presented during the first year after the transplant. Results: Of the 16 patients evaluated, 62.5% were under 1 year of age, with a median weight of 7.4kg, 50% presented a CHILD C score, with a median PELD of 23, the main reason for transplantation was atresia of bile ducts (62.5%), the main complications prior to transplantation were portal hypertension (75%) and malnutrition (68.8%). All posttransplant patients presented at least one infectious complication: bacterial (53%), CMV infection (75%) and EBV infection (31%); Regarding vascular complications, 25% presented portal vein thrombosis and one patient (6%) presented hepatic artery stenosis; Regarding biliary complications, 12.5% presented biliary fistula, also 12.5% presented bile duct dilation, while 6.25% presented bilioma. Conclusions: Among the main complications of the postliver transplant patient, we can highlight that all patients presented at least one infectious complication (100%), vascular complications in 31% and biliary complications in 31.25% of patients.Objetivo: Determinar las complicaciones durante el primer año post trasplante hepático en pacientes pediátricos del Instituto Nacional de Salud del Niño-San Borja (INSN-SB) durante el periodo 2016-2020. Materiales y métodos: Estudio descriptivo, transversal. Se revisaron las historias clínicas de los pacientes trasplantados hepáticos atendidos durante el seguimiento post trasplante en el INSN SB recolectándose características epidemiológicas, indicación de trasplante; puntaje PELD, score CHILD y complicaciones previas al trasplante, así como la frecuencia de las principales complicaciones presentadas durante el primer año post trasplante. Resultados: De los 16 pacientes evaluados, el 62,5% fueron menores de 1 año, siendo la mediana de peso 7,4 kg, el 50% presentó un score CHILD C, la mediana de PELD de 23. El principal motivo de trasplante fue atresia de vías biliares (62,5%). Las principales complicaciones previas al trasplante fueron la hipertensión portal (75%) y la desnutrición (68,8%). Todos los pacientes post trasplantados presentaron al menos una complicación infecciosa: bacteriana (53%), infección por CMV (75%) e infección por EBV (31%); en relación a las complicaciones vasculares, 25% presentaron  trombosis de vena porta y un paciente (6%) presentó estenosis de arteria hepática; con respecto a las  complicaciones biliares, el 12,5% presentaron fístula biliar, también el 12,5% presentaron  dilatación de la vía biliar, mientras que el 6,25% presentó bilioma. Conclusiones: Dentro de las principales complicaciones del paciente post trasplantado hepático podemos destacar que todos los pacientes presentaron al menos una complicación infecciosa (100%), complicaciones vasculares el 31% y complicaciones biliares en el 31,25% de los pacientes.Sociedad de Gastroenterología del Perú2024-06-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistagastroperu.com/index.php/rgp/article/view/1606Revista de Gastroenterología del Perú; Vol. 44 No. 2 (2024)Revista de Gastroenterología del Perú; Vol. 44 Núm. 2 (2024)1609-722X1022-5129reponame:Revista de Gastroenterología del Perúinstname:Sociedad de Gastroenterología del Perúinstacron:SOCIOGASTROspahttps://revistagastroperu.com/index.php/rgp/article/view/1606/1242Derechos de autor 2024 Rosa Castro-Johanson, Gabriela Tello Quispe, Rodrigo Verastegui S., Diana Perez Rodriguezhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:ojs.revistagastroperu.com:article/16062025-04-11T20:17:24Z
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