Prognostic Value Of Fetal Urinary Beta-2 Microglobuline In Vesicoamniotic Shunting Therapy For Fetal Obstructive Uropathy

• Autores: Gil-Guevara, Enrique Damián, Diaz, Ramiro, Bermudez, Carlos
• Formato: artículo
• Fecha de Publicación: 2017
• Institución: Instituto Nacional Materno Perinatal
• Repositorio: Revista Peruana de Investigación Materno Perinatal
• Lenguaje: español
• OAI Identifier: oai:ojs.www.fracturae.com:article/71
• Enlace del recurso: https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/71
• Nivel de acceso: acceso abierto
• Materia: Fetal obstructive uropathy; Beta 2 microglobuline; Vesicoamniotic shunt therapy; Uropatía obstructiva fetal; Beta 2 microglobulina; Terapia de derivación vesicoamniotica

Introduction and objectives. Fetal obstructive uropathy can be treated early in pregnancy by intrauterine vesicoamnioticshunting, immediately after being diagnosed by ultrasound, in specific cases with a favorable prognosis in renal function usingfetal urinary beta-2 microglobuline. The main objective of the study was to determine the changes of beta-2 microglobulinein consecutive samples of fetal urine in 48 – 72 hour-intervals in fetuses with obstructive uropathy at 16 weeks of gestation.Methods. We performed a descriptive and longitudinal study, including 15 pregnant women whose fetuses were diagnosedwith obstructive uropathy and without chromosomal abnormalities, performing vesicocentesis for urinary biometry.