Testicular infiltration due to acute lymphoblastic leukemia presented as a testicular mass: A case report

• Autores: Herrera-Lomonaco, Sandra, Cabeza-Morales, Marticela, Angulo-Díaz, Indira, Carmona-Meza, Zenen, Corrales-Santander, Hugo Rafael
• Formato: artículo
• Fecha de Publicación: 2017
• Institución: Universidad de San Martín de Porres
• Repositorio: Horizonte médico
• Lenguaje: español
• OAI Identifier: oai:horizontemedico.usmp.edu.pe:article/563
• Enlace del recurso: https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/563
• Nivel de acceso: acceso abierto
• Materia: Leucemia-linfoma linfoblástico; Neoplasias testiculares; Leucemia; Lymphoblastic leukemia/lymphoma; Testicular neoplasia; Leukemia

Acute lymphoblastic leukemia is a common pediatric neoplasia, comprising 11% of all leukemias. In Colombia, the annual incidence in adults is 1 out of 100,000 people. Testicular relapse is rare (accounting for only 0.9-8.8% of all cases) and represents a sign of recurrence which can be confused with other testicular conditions. We report the case of a 23-yearold male with testicular pain and swelling for 2 months after a trauma, and a history of acute lymphoblastic leukemia treated 4 years before. A testicular ultrasound suggested tension hydrocele. The patient was taken to surgery where a testis with neoplastic features was observed. Therefore, an orchiectomy was performed. The pathological anatomy revealed a 12-cm mass consisting of infiltration by leukemic cells, showing a positive expression for CD19, CD10, and a negative expression for TdT. The testes are considered a sanctuary site for leukemic cells. However, the formation of a mass that mimic a testicular tumor may exceptionally be observed.