Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007
Descripción del Articulo
Introduction: Bexarotene is a rexinoid compound that is approved for use in the therapy for early and advanced stage cutaneous T-cell lymphoma (CTCL).Clinical Cases: We present in this report the results of the use of low-dose bexarotene plus phototherapy or alpha-interferon, nine...
| Autores: | , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2018 |
| Institución: | Colegio Médico del Perú |
| Repositorio: | Acta Médica Peruana |
| Lenguaje: | español |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/2643 |
| Enlace del recurso: | https://amp.cmp.org.pe/index.php/AMP/article/view/2643 |
| Nivel de acceso: | acceso abierto |
| Materia: | Cutaneous T-cell lymphoma bexarotene alpha-interferon |
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Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007Tratamiento del linfoma cutáneo de células T con bexaroteno a dosis bajas en combinación con fototerapia o interferon alfa: comunicación de ocho casos tratados en el Hospital Edgardo Rebagliati Martins, 2003-2007, Lima, PerúBeltrán Gárate, BradyParedes Arcos, AntonioMoisés Alfaro, CeliaSanchez Félix, GadwinRiva Gonzales, LuisHurtado de Mendoza, FernandoCotrina Montenegro, EstherSalas Rojas, RenzoCutaneous T-cell lymphomabexarotenealpha-interferonIntroduction: Bexarotene is a rexinoid compound that is approved for use in the therapy for early and advanced stage cutaneous T-cell lymphoma (CTCL).Clinical Cases: We present in this report the results of the use of low-dose bexarotene plus phototherapy or alpha-interferon, nine million units, in the treatment of CTCL. Eight patients were treated, five had mycosis fungoides, two had CD-8 epidermothropic aggressive lymphoma. The overall response rate was 62.5% (5/8), and the mean duration of response was 20 months. Low-dose bexarotene combined with phototherapy or alpha-interferon may be effective in the treatment of CTCL.Introducción: bexaroteno es un rexinoide aprobado en el tratamiento de estadios tempranos y avanzados del linfoma cutáneo de células T (LCCT).Caso Clínico: el presente reporte de casos mostramos los resultados del empleo de bexaroteno en dosis bajas más fototerapia o Interferon alfa 9 millones en el tratamiento del LCCT. Ocho pacientes fueron tratados, cinco fueron Micosis fungoides, dos Linfoma Epidermotrópico CD8 agresivo y uno fue un Síndrome Sézary. La respuesta global fue del 62.5% (5/8) y la duración media de respuesta fue de 20 meses. El bexaroteno en dosis bajas en combinación a fototerapia o interferon alfa 2a puede ser efectivo en el tratamiento del LCCT.Colegio Médico del Perú2018-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://amp.cmp.org.pe/index.php/AMP/article/view/2643ACTA MEDICA PERUANA; Vol 25 No 4 (2008); 232-235ACTA MEDICA PERUANA; Vol. 25 Núm. 4 (2008); 232-2351728-59171018-8800reponame:Acta Médica Peruanainstname:Colegio Médico del Perúinstacron:CMPspahttps://amp.cmp.org.pe/index.php/AMP/article/view/2643/1540Copyright (c) 2023 ACTA MEDICA PERUANAinfo:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/26432023-07-06T05:52:11Z |
| dc.title.none.fl_str_mv |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 Tratamiento del linfoma cutáneo de células T con bexaroteno a dosis bajas en combinación con fototerapia o interferon alfa: comunicación de ocho casos tratados en el Hospital Edgardo Rebagliati Martins, 2003-2007, Lima, Perú |
| title |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 |
| spellingShingle |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 Beltrán Gárate, Brady Cutaneous T-cell lymphoma bexarotene alpha-interferon |
| title_short |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 |
| title_full |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 |
| title_fullStr |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 |
| title_full_unstemmed |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 |
| title_sort |
Therapy for cutaneous T-cell lymphoma using low-dose bexarotene combined with phototherapy or alpha-interferon: Report of eight cases treated in Hospital Nacional Edgardo Rebagliati-Martins, Lima, Peru between 2003 and 2007 |
| dc.creator.none.fl_str_mv |
Beltrán Gárate, Brady Paredes Arcos, Antonio Moisés Alfaro, Celia Sanchez Félix, Gadwin Riva Gonzales, Luis Hurtado de Mendoza, Fernando Cotrina Montenegro, Esther Salas Rojas, Renzo |
| author |
Beltrán Gárate, Brady |
| author_facet |
Beltrán Gárate, Brady Paredes Arcos, Antonio Moisés Alfaro, Celia Sanchez Félix, Gadwin Riva Gonzales, Luis Hurtado de Mendoza, Fernando Cotrina Montenegro, Esther Salas Rojas, Renzo |
| author_role |
author |
| author2 |
Paredes Arcos, Antonio Moisés Alfaro, Celia Sanchez Félix, Gadwin Riva Gonzales, Luis Hurtado de Mendoza, Fernando Cotrina Montenegro, Esther Salas Rojas, Renzo |
| author2_role |
author author author author author author author |
| dc.subject.none.fl_str_mv |
Cutaneous T-cell lymphoma bexarotene alpha-interferon |
| topic |
Cutaneous T-cell lymphoma bexarotene alpha-interferon |
| description |
Introduction: Bexarotene is a rexinoid compound that is approved for use in the therapy for early and advanced stage cutaneous T-cell lymphoma (CTCL).Clinical Cases: We present in this report the results of the use of low-dose bexarotene plus phototherapy or alpha-interferon, nine million units, in the treatment of CTCL. Eight patients were treated, five had mycosis fungoides, two had CD-8 epidermothropic aggressive lymphoma. The overall response rate was 62.5% (5/8), and the mean duration of response was 20 months. Low-dose bexarotene combined with phototherapy or alpha-interferon may be effective in the treatment of CTCL. |
| publishDate |
2018 |
| dc.date.none.fl_str_mv |
2018-06-30 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://amp.cmp.org.pe/index.php/AMP/article/view/2643 |
| url |
https://amp.cmp.org.pe/index.php/AMP/article/view/2643 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://amp.cmp.org.pe/index.php/AMP/article/view/2643/1540 |
| dc.rights.none.fl_str_mv |
Copyright (c) 2023 ACTA MEDICA PERUANA info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Copyright (c) 2023 ACTA MEDICA PERUANA |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Colegio Médico del Perú |
| publisher.none.fl_str_mv |
Colegio Médico del Perú |
| dc.source.none.fl_str_mv |
ACTA MEDICA PERUANA; Vol 25 No 4 (2008); 232-235 ACTA MEDICA PERUANA; Vol. 25 Núm. 4 (2008); 232-235 1728-5917 1018-8800 reponame:Acta Médica Peruana instname:Colegio Médico del Perú instacron:CMP |
| instname_str |
Colegio Médico del Perú |
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CMP |
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CMP |
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Acta Médica Peruana |
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Acta Médica Peruana |
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1816075113101000704 |
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13.957789 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
