Impact of albumin on the survival of elderly patients with diffuse large B cell lymphoma

• Autor: Beltran, Brady E.
• Formato: artículo
• Fecha de Publicación: 2025
• Institución: Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Repositorio: Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Lenguaje: español
• OAI Identifier: oai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/2215
• Enlace del recurso: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/2215
• Nivel de acceso: acceso abierto
• Materia: Linfoma células grandes B difuso; albúmina; ancianos; Diffuse large B cell lymphoma; Albumin; Elderly

Introduction: Diffuse large B cell lymphoma is the most common subtype of lymphoma. Albumin proves to be a prognostic factor in this subtype of lymphoma. Objective: The objective of this study is to evaluate the role of albumin in the survival of elderly patients with diffuse large B cell lymphoma  in a hospital in Peru. Material and methods: This was a retrospective study of 62 patients with diffuse large B cell lymphoma aged 80 or older. Results: In the multivariate analysis, bulky disease (HR= 3.1, 95% 1.5-6.4; p=0.003) and albumin (HR 3.8, 95% 1.9-7.6; p=0.001) were factors associated with survival. Conclusions: bulky disease and albumin were factors associated with overall survival in patients with diffuse large B cell lymphoma aged 80 or older.