Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer

Descripción del Articulo

Prostate cancer, although the second most common cancer in men, does not have established biomarkers to predict the risk of relapse and risk of presenting biochemical recurrence. A deeper comprehension of tissue behavior provided by molecular techniques m
Detalles Bibliográficos
Autor: Marin, Laura Elise
Formato: tesis doctoral
Fecha de Publicación:2024
Institución:Pontificia Universidad Católica del Perú
Repositorio:PUCP-Tesis
Lenguaje:inglés
OAI Identifier:oai:tesis.pucp.edu.pe:20.500.12404/30392
Enlace del recurso:http://hdl.handle.net/20.500.12404/30392
Nivel de acceso:acceso abierto
Materia:Próstata--Cáncer
Biomarcadores
Aprendizaje automático (Inteligencia artificial)
Fenotipo
Genoma humano
https://purl.org/pe-repo/ocde/ford#2.00.00
id PUCP_91d0a8424533106a7921684bfe9b6caf
oai_identifier_str oai:tesis.pucp.edu.pe:20.500.12404/30392
network_acronym_str PUCP
network_name_str PUCP-Tesis
repository_id_str .
dc.title.en_EN.fl_str_mv Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
title Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
spellingShingle Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
Marin, Laura Elise
Próstata--Cáncer
Biomarcadores
Aprendizaje automático (Inteligencia artificial)
Fenotipo
Genoma humano
https://purl.org/pe-repo/ocde/ford#2.00.00
title_short Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
title_full Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
title_fullStr Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
title_full_unstemmed Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
title_sort Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancer
author Marin, Laura Elise
author_facet Marin, Laura Elise
author_role author
dc.contributor.advisor.fl_str_mv Casado Peña, Fanny Lys
dc.contributor.author.fl_str_mv Marin, Laura Elise
dc.subject.es_ES.fl_str_mv Próstata--Cáncer
Biomarcadores
Aprendizaje automático (Inteligencia artificial)
Fenotipo
Genoma humano
topic Próstata--Cáncer
Biomarcadores
Aprendizaje automático (Inteligencia artificial)
Fenotipo
Genoma humano
https://purl.org/pe-repo/ocde/ford#2.00.00
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#2.00.00
description Prostate cancer, although the second most common cancer in men, does not have established biomarkers to predict the risk of relapse and risk of presenting biochemical recurrence. A deeper comprehension of tissue behavior provided by molecular techniques m
publishDate 2024
dc.date.created.none.fl_str_mv 2024
dc.date.accessioned.none.fl_str_mv 2025-04-01T17:50:05Z
dc.date.issued.fl_str_mv 2025-04-01
dc.type.none.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12404/30392
url http://hdl.handle.net/20.500.12404/30392
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.fl_str_mv SUNEDU
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv http://creativecommons.org/licenses/by/2.5/pe/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.5/pe/
dc.publisher.es_ES.fl_str_mv Pontificia Universidad Católica del Perú
dc.publisher.country.none.fl_str_mv PE
dc.source.none.fl_str_mv reponame:PUCP-Tesis
instname:Pontificia Universidad Católica del Perú
instacron:PUCP
instname_str Pontificia Universidad Católica del Perú
instacron_str PUCP
institution PUCP
reponame_str PUCP-Tesis
collection PUCP-Tesis
bitstream.url.fl_str_mv https://tesis.pucp.edu.pe/bitstreams/831f322f-aaa0-46e8-8d6f-fdbd22d18537/download
https://tesis.pucp.edu.pe/bitstreams/298cfe0b-3dfd-4971-9d93-6e616782f3f9/download
https://tesis.pucp.edu.pe/bitstreams/adbf218d-ee3f-406e-84ed-11d93f9aa721/download
https://tesis.pucp.edu.pe/bitstreams/2ae16c5d-558c-49ba-bfa6-376b47b1e907/download
https://tesis.pucp.edu.pe/bitstreams/1f2cac7a-a46d-4eba-9809-71ab3168ae08/download
https://tesis.pucp.edu.pe/bitstreams/26649c03-4d96-48ee-9bef-13f3a183171f/download
https://tesis.pucp.edu.pe/bitstreams/e0ad9202-0cdd-4cbb-a955-c6cc5a606cfe/download
https://tesis.pucp.edu.pe/bitstreams/8a10b487-7c75-416e-82bc-8c28d929df37/download
bitstream.checksum.fl_str_mv dd1e64bf0b1aac5b353b23c880f3b4b5
e60d03935f6024f0fd00aa67e9712242
bb9bdc0b3349e4284e09149f943790b4
48725b7f9a634bc551f52084693052d1
3edc873fc5c0a88d520dd594af5ed6f3
d81d9bf50aee5a15e6b8879e1a57797c
b8bca2b4e34c9058ce9a67f78799466b
52eb959c4962f267991ec4de33ef072b
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio de Tesis PUCP
repository.mail.fl_str_mv raul.sifuentes@pucp.pe
_version_ 1834736816704454656
spelling Casado Peña, Fanny LysMarin, Laura Elise2025-04-01T17:50:05Z20242025-04-01http://hdl.handle.net/20.500.12404/30392Prostate cancer, although the second most common cancer in men, does not have established biomarkers to predict the risk of relapse and risk of presenting biochemical recurrence. A deeper comprehension of tissue behavior provided by molecular techniques mengPontificia Universidad Católica del PerúPEinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/pe/Próstata--CáncerBiomarcadoresAprendizaje automático (Inteligencia artificial)FenotipoGenoma humanohttps://purl.org/pe-repo/ocde/ford#2.00.00Integrative digital pathology for personalized medicine: population stratification and early biomarkers findings, consolidating and completing the use of Prostate-Specific Antigen (PSA) and Gleason Score in prostate cancerinfo:eu-repo/semantics/doctoralThesisreponame:PUCP-Tesisinstname:Pontificia Universidad Católica del Perúinstacron:PUCPSUNEDUDoctor en IngenieríaDoctoradoPontificia Universidad Católica del Perú. Escuela de PosgradoIngeniería40444557https://orcid.org/0000-0002-8791-626X20EA60320732028Andrade Navarro, Miguel AngelCasado Peña, Fanny LysRacoceanu, DanielTamez Peña, José GerardoCastañeda Aphan, Benjamínhttps://purl.org/pe-repo/renati/level#doctorhttps://purl.org/pe-repo/renati/type#tesisORIGINALMARIN_LAURA_ELISE.pdfMARIN_LAURA_ELISE.pdfTexto completoapplication/pdf5401678https://tesis.pucp.edu.pe/bitstreams/831f322f-aaa0-46e8-8d6f-fdbd22d18537/downloaddd1e64bf0b1aac5b353b23c880f3b4b5MD51trueAnonymousREADMARIN_LAURA_ELISE_T.pdfMARIN_LAURA_ELISE_T.pdfReporte de originalidadapplication/pdf43015387https://tesis.pucp.edu.pe/bitstreams/298cfe0b-3dfd-4971-9d93-6e616782f3f9/downloade60d03935f6024f0fd00aa67e9712242MD52falseAdministratorREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://tesis.pucp.edu.pe/bitstreams/adbf218d-ee3f-406e-84ed-11d93f9aa721/downloadbb9bdc0b3349e4284e09149f943790b4MD53falseAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81025https://tesis.pucp.edu.pe/bitstreams/2ae16c5d-558c-49ba-bfa6-376b47b1e907/download48725b7f9a634bc551f52084693052d1MD54falseAnonymousREADTEXTMARIN_LAURA_ELISE.pdf.txtMARIN_LAURA_ELISE.pdf.txtExtracted texttext/plain264305https://tesis.pucp.edu.pe/bitstreams/1f2cac7a-a46d-4eba-9809-71ab3168ae08/download3edc873fc5c0a88d520dd594af5ed6f3MD55falseAnonymousREADMARIN_LAURA_ELISE_T.pdf.txtMARIN_LAURA_ELISE_T.pdf.txtExtracted texttext/plain21788https://tesis.pucp.edu.pe/bitstreams/26649c03-4d96-48ee-9bef-13f3a183171f/downloadd81d9bf50aee5a15e6b8879e1a57797cMD57falseAdministratorREADTHUMBNAILMARIN_LAURA_ELISE.pdf.jpgMARIN_LAURA_ELISE.pdf.jpgGenerated Thumbnailimage/jpeg8968https://tesis.pucp.edu.pe/bitstreams/e0ad9202-0cdd-4cbb-a955-c6cc5a606cfe/downloadb8bca2b4e34c9058ce9a67f78799466bMD56falseAnonymousREADMARIN_LAURA_ELISE_T.pdf.jpgMARIN_LAURA_ELISE_T.pdf.jpgGenerated Thumbnailimage/jpeg18100https://tesis.pucp.edu.pe/bitstreams/8a10b487-7c75-416e-82bc-8c28d929df37/download52eb959c4962f267991ec4de33ef072bMD58falseAdministratorREAD20.500.12404/30392oai:tesis.pucp.edu.pe:20.500.12404/303922025-04-21 16:47:11.318http://creativecommons.org/licenses/by/2.5/pe/info:eu-repo/semantics/openAccessopen.accesshttps://tesis.pucp.edu.peRepositorio de Tesis PUCPraul.sifuentes@pucp.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
score 13.987529
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).