Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon

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Funding: This research was funded by the Project Concytec – Banco Mundial “Mejoramiento y Ampliación de los Servicios del Sistema Nacional de Ciencia Tecnología e Innovación Tecnológica” 8682, through its executing unit Fondecyt [Contrato N° 119-2018-FONDECYT-BM-IADT-MU]. M. J. S acknowledge fondecy...

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Autores: Vargas-arana G., Merino-zegarra C., Riquelme-penaherrera M., Nonato-ramirez L., Delgado-wong H., Pertino M.W., Parra C., Simirgiotis M.J.J.
Formato: artículo
Fecha de Publicación:2021
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/2970
Enlace del recurso:https://hdl.handle.net/20.500.12390/2970
https://doi.org/10.3390/antiox10101566
Nivel de acceso:acceso abierto
Materia:UHPLC-PDA-ESI-OT-MS
Antihyperlipidemic
Antioxidant activity
Nutritional values
Phenolics
Solanaceae
https://purl.org/pe-repo/ocde/ford#3.03.04
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network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
title Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
spellingShingle Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
Vargas-arana G.
UHPLC-PDA-ESI-OT-MS
Antihyperlipidemic
Antihyperlipidemic
Antioxidant activity
Antioxidant activity
Nutritional values
Phenolics
Solanaceae
Solanaceae
https://purl.org/pe-repo/ocde/ford#3.03.04
title_short Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
title_full Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
title_fullStr Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
title_full_unstemmed Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
title_sort Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
author Vargas-arana G.
author_facet Vargas-arana G.
Merino-zegarra C.
Riquelme-penaherrera M.
Nonato-ramirez L.
Delgado-wong H.
Pertino M.W.
Parra C.
Simirgiotis M.J.J.
author_role author
author2 Merino-zegarra C.
Riquelme-penaherrera M.
Nonato-ramirez L.
Delgado-wong H.
Pertino M.W.
Parra C.
Simirgiotis M.J.J.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vargas-arana G.
Merino-zegarra C.
Riquelme-penaherrera M.
Nonato-ramirez L.
Delgado-wong H.
Pertino M.W.
Parra C.
Simirgiotis M.J.J.
dc.subject.none.fl_str_mv UHPLC-PDA-ESI-OT-MS
topic UHPLC-PDA-ESI-OT-MS
Antihyperlipidemic
Antihyperlipidemic
Antioxidant activity
Antioxidant activity
Nutritional values
Phenolics
Solanaceae
Solanaceae
https://purl.org/pe-repo/ocde/ford#3.03.04
dc.subject.es_PE.fl_str_mv Antihyperlipidemic
Antihyperlipidemic
Antioxidant activity
Antioxidant activity
Nutritional values
Phenolics
Solanaceae
Solanaceae
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.03.04
description Funding: This research was funded by the Project Concytec – Banco Mundial “Mejoramiento y Ampliación de los Servicios del Sistema Nacional de Ciencia Tecnología e Innovación Tecnológica” 8682, through its executing unit Fondecyt [Contrato N° 119-2018-FONDECYT-BM-IADT-MU]. M. J. S acknowledge fondecyt 1180059.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/2970
dc.identifier.doi.none.fl_str_mv https://doi.org/10.3390/antiox10101566
dc.identifier.scopus.none.fl_str_mv 2-s2.0-85116075201
url https://hdl.handle.net/20.500.12390/2970
https://doi.org/10.3390/antiox10101566
identifier_str_mv 2-s2.0-85116075201
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Antioxidants
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844883040250101760
spelling Publicationrp08414600rp08416600rp08420600rp08418600rp08413600rp08415600rp08419600rp08417600Vargas-arana G.Merino-zegarra C.Riquelme-penaherrera M.Nonato-ramirez L.Delgado-wong H.Pertino M.W.Parra C.Simirgiotis M.J.J.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2021https://hdl.handle.net/20.500.12390/2970https://doi.org/10.3390/antiox101015662-s2.0-85116075201Funding: This research was funded by the Project Concytec – Banco Mundial “Mejoramiento y Ampliación de los Servicios del Sistema Nacional de Ciencia Tecnología e Innovación Tecnológica” 8682, through its executing unit Fondecyt [Contrato N° 119-2018-FONDECYT-BM-IADT-MU]. M. J. S acknowledge fondecyt 1180059.Cocona fruits are a popular food and medicinal fruit used mainly in the Amazon and several countries of South America for the preparation of several food products such as drinks, jams and milk shakes. In this study five ecotypes of cocona native to Peru have been studied regarding their nutritional and antioxidants values plus antihyperlipidemic activities. Seventy bioactive compounds have been detected in Peruvian cocona ecotypes including several phenolic acids, aminoacids and flavonoids; of those six were spermidines, (peaks 1, 2, 25, 26, 38 and 39), thirteen were aminoacids, (peaks 3,-9, 11-13, 16, 17, 22-24), eighteen flavonoids (peaks 28, 30-32 45,46, 48-53 56, 57, 61 and 64-66), twelve were phenolics (peaks 19, 21, 27, 29, 34, 35, 36, 42, 43, 44, 54, and 59), two carotenoids, (peak 62 and 63), eight were lipid derivatives (peaks 37, 55, 58, 60 and 67-70), one sugar (peak 47), four terpenes (peaks 33, 40, 41 and 47), two amides, (peaks 10 and 18), one aldehyde, (peak 15), and three saturated organic acids, (peaks 4, 5 and 20). Hypercholesterolemic rats administered with pulp of the ecotypes CTR and SRN9 showed the lowest cholesterol and triglyceride levels after treatment (126.74 ± 6.63; 102.11 ± 9.47; 58.16 ± 6.64; 61.05 ± 4.00 mg/dL, for cholesterol, triglycerides, high-density lipoprotein and low-density lipoprotein respectively, for the group treated with SRN9 pulp, and 130.09 ± 8.55; 108.51 ± 10.04; 57.30 ± 5.72; and 65.41 ± 7.68 mg/dL, for cholesterol, triglycerides, HDL and LDL lipoproteins respectively for the group treated with CTR pulp). The ecotypes proved to be good sources of natural antioxidants and their consumption represent an alternative for the prevention of atherosclerosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengMDPIAntioxidantsinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/UHPLC-PDA-ESI-OT-MSAntihyperlipidemic-1Antihyperlipidemic-1Antioxidant activity-1Antioxidant activity-1Nutritional values-1Phenolics-1Solanaceae-1Solanaceae-1https://purl.org/pe-repo/ocde/ford#3.03.04-1Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazoninfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/2970oai:repositorio.concytec.gob.pe:20.500.12390/29702024-05-30 16:12:39.416https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="deffe4a5-82dc-476f-915c-f567490679ff"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon</Title> <PublishedIn> <Publication> <Title>Antioxidants</Title> </Publication> </PublishedIn> <PublicationDate>2021</PublicationDate> <DOI>https://doi.org/10.3390/antiox10101566</DOI> <SCP-Number>2-s2.0-85116075201</SCP-Number> <Authors> <Author> <DisplayName>Vargas-arana G.</DisplayName> <Person id="rp08414" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Merino-zegarra C.</DisplayName> <Person id="rp08416" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Riquelme-penaherrera M.</DisplayName> <Person id="rp08420" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Nonato-ramirez L.</DisplayName> <Person id="rp08418" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Delgado-wong H.</DisplayName> <Person id="rp08413" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Pertino M.W.</DisplayName> <Person id="rp08415" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Parra C.</DisplayName> <Person id="rp08419" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Simirgiotis M.J.J.</DisplayName> <Person id="rp08417" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>MDPI</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by-nc-nd/4.0/</License> <Keyword>UHPLC-PDA-ESI-OT-MS</Keyword> <Keyword>Antihyperlipidemic</Keyword> <Keyword>Antihyperlipidemic</Keyword> <Keyword>Antioxidant activity</Keyword> <Keyword>Antioxidant activity</Keyword> <Keyword>Nutritional values</Keyword> <Keyword>Phenolics</Keyword> <Keyword>Solanaceae</Keyword> <Keyword>Solanaceae</Keyword> <Abstract>Cocona fruits are a popular food and medicinal fruit used mainly in the Amazon and several countries of South America for the preparation of several food products such as drinks, jams and milk shakes. In this study five ecotypes of cocona native to Peru have been studied regarding their nutritional and antioxidants values plus antihyperlipidemic activities. Seventy bioactive compounds have been detected in Peruvian cocona ecotypes including several phenolic acids, aminoacids and flavonoids; of those six were spermidines, (peaks 1, 2, 25, 26, 38 and 39), thirteen were aminoacids, (peaks 3,-9, 11-13, 16, 17, 22-24), eighteen flavonoids (peaks 28, 30-32 45,46, 48-53 56, 57, 61 and 64-66), twelve were phenolics (peaks 19, 21, 27, 29, 34, 35, 36, 42, 43, 44, 54, and 59), two carotenoids, (peak 62 and 63), eight were lipid derivatives (peaks 37, 55, 58, 60 and 67-70), one sugar (peak 47), four terpenes (peaks 33, 40, 41 and 47), two amides, (peaks 10 and 18), one aldehyde, (peak 15), and three saturated organic acids, (peaks 4, 5 and 20). Hypercholesterolemic rats administered with pulp of the ecotypes CTR and SRN9 showed the lowest cholesterol and triglyceride levels after treatment (126.74 ± 6.63; 102.11 ± 9.47; 58.16 ± 6.64; 61.05 ± 4.00 mg/dL, for cholesterol, triglycerides, high-density lipoprotein and low-density lipoprotein respectively, for the group treated with SRN9 pulp, and 130.09 ± 8.55; 108.51 ± 10.04; 57.30 ± 5.72; and 65.41 ± 7.68 mg/dL, for cholesterol, triglycerides, HDL and LDL lipoproteins respectively for the group treated with CTR pulp). The ecotypes proved to be good sources of natural antioxidants and their consumption represent an alternative for the prevention of atherosclerosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
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