Isolation and characterization of a fibrinogen-clotting enzyme from venom of the snake, Lachesis muta muta(Peruvian bushmaster)

• Autores: Yarleque A., Campos S., Escobar E., Lazo F., Sanchez N., Hyslop S., Marsh N.A., Butterworth P.J., Price R.G.
• Formato: artículo
• Fecha de Publicación: 1989
• Institución: Consejo Nacional de Ciencia Tecnología e Innovación
• Repositorio: CONCYTEC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorio.concytec.gob.pe:20.500.12390/802
• Enlace del recurso: https://hdl.handle.net/20.500.12390/802; https://doi.org/10.1016/0041-0101(89)90027-5
• Nivel de acceso: acceso abierto
• Materia: snake venom; enzyme; animal cell; blood clotting; defibrinogenation; enzyme isolation; nonhuman; reptile; Amino Acids; Animal; Blood Coagulation; Chromatography; https://purl.org/pe-repo/ocde/ford#4.02.00

A. Yarleque, S. Campos, E. Escobar, F. Lazo, N. Sanchez, S. Hyslop, N. A. Marsh, P. J. Butterworth and R. G. Price. Isolation and characterization of a fibrinogen-clotting enzyme from venom of the snake Lachesis muta muta(Peruvian bushmaster). Toxicon27, 1189–1197, 1989.—A fibrinogen-clotting enzyme from the venom of the Peruvian bushmaster snake was purified to homogeneity by gel filtration on Sephadex G-100 followed by DEAE-cellulose ion-exchange chromatography using a linear ionic strength gradient with NaCl.