HP and EBVaGC in Peruvian patients

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Gastric cancer (GC) is the second most common cancer and first leading cause of cancer-related deaths in Peru. Infection by Helicobacter pylori (HP) and Epstein-Barr virus (EBV) are accepted carcinogenic and infection is widely spread in the Peruvian population. The aims of this study were to evalua...

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Detalles Bibliográficos
Autores: Lopez, CB, Garcia, MC, Altamirano, CAC, Bolanos, LFB, Leonardo, D, Meza, EP, Bernaola, VV, Prado, JN, Sifuentes, JRS, Monsalve, LAB, Sanchez, MACLR, Dionisio, OM, Passiuri, IC
Formato: objeto de conferencia
Fecha de Publicación:2018
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/1079
Enlace del recurso:https://hdl.handle.net/20.500.12390/1079
https://doi.org/10.1158/1538-7445.AM2018-4210
Nivel de acceso:acceso abierto
Materia:Helicobacter pylori
Gastric cancer
Epstein-Barr virus
https://purl.org/pe-repo/ocde/ford#3.02.21
id CONC_2e687b1e1e2ac7ce0066e17274ae1446
oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/1079
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv HP and EBVaGC in Peruvian patients
title HP and EBVaGC in Peruvian patients
spellingShingle HP and EBVaGC in Peruvian patients
Lopez, CB
Helicobacter pylori
Gastric cancer
Epstein-Barr virus
https://purl.org/pe-repo/ocde/ford#3.02.21
title_short HP and EBVaGC in Peruvian patients
title_full HP and EBVaGC in Peruvian patients
title_fullStr HP and EBVaGC in Peruvian patients
title_full_unstemmed HP and EBVaGC in Peruvian patients
title_sort HP and EBVaGC in Peruvian patients
author Lopez, CB
author_facet Lopez, CB
Garcia, MC
Altamirano, CAC
Bolanos, LFB
Leonardo, D
Meza, EP
Bernaola, VV
Prado, JN
Sifuentes, JRS
Monsalve, LAB
Sanchez, MACLR
Dionisio, OM
Passiuri, IC
author_role author
author2 Garcia, MC
Altamirano, CAC
Bolanos, LFB
Leonardo, D
Meza, EP
Bernaola, VV
Prado, JN
Sifuentes, JRS
Monsalve, LAB
Sanchez, MACLR
Dionisio, OM
Passiuri, IC
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lopez, CB
Garcia, MC
Altamirano, CAC
Bolanos, LFB
Leonardo, D
Meza, EP
Bernaola, VV
Prado, JN
Sifuentes, JRS
Monsalve, LAB
Sanchez, MACLR
Dionisio, OM
Passiuri, IC
dc.subject.none.fl_str_mv Helicobacter pylori
topic Helicobacter pylori
Gastric cancer
Epstein-Barr virus
https://purl.org/pe-repo/ocde/ford#3.02.21
dc.subject.es_PE.fl_str_mv Gastric cancer
Epstein-Barr virus
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.02.21
description Gastric cancer (GC) is the second most common cancer and first leading cause of cancer-related deaths in Peru. Infection by Helicobacter pylori (HP) and Epstein-Barr virus (EBV) are accepted carcinogenic and infection is widely spread in the Peruvian population. The aims of this study were to evaluate HP and EBV-associated GC (EBVaCG), to assess the prevalence rate and to define the characteristics of Peruvian patients. GC samples were prospectively collected from patients who underwent gastroscopy or surgical resection with no preoperative treatment at INEN between 2015 and 2017. Tumor tissue (T), proximal healthy tissue (P) and distal healthy tissue (D) samples were assessed for HP and EBV by quantitative PCR (qPCR) using specific primers. HP and EBV status were analyzed along with clinicopathologic parameters of the tumor. Kaplan-Meier estimation curves overall survival (OS) was applied. Comparison between qPCR detection and current standard methods of detection was also performed. All tests were two sided, and a p≤0.05 was considered statistically significant.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/1079
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1158/1538-7445.AM2018-4210
dc.identifier.isi.none.fl_str_mv 468819502407
url https://hdl.handle.net/20.500.12390/1079
https://doi.org/10.1158/1538-7445.AM2018-4210
identifier_str_mv 468819502407
dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Association for Cancer Research
publisher.none.fl_str_mv American Association for Cancer Research
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
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spelling Publicationrp03062600rp02711500rp03068600rp03066600rp03063600rp03061600rp03070600rp03067600rp03064600rp03065600rp03071600rp03069600rp03072600Lopez, CBGarcia, MCAltamirano, CACBolanos, LFBLeonardo, DMeza, EPBernaola, VVPrado, JNSifuentes, JRSMonsalve, LABSanchez, MACLRDionisio, OMPassiuri, IC2024-05-30T23:13:38Z2024-05-30T23:13:38Z2018https://hdl.handle.net/20.500.12390/1079https://doi.org/10.1158/1538-7445.AM2018-4210468819502407Gastric cancer (GC) is the second most common cancer and first leading cause of cancer-related deaths in Peru. Infection by Helicobacter pylori (HP) and Epstein-Barr virus (EBV) are accepted carcinogenic and infection is widely spread in the Peruvian population. The aims of this study were to evaluate HP and EBV-associated GC (EBVaCG), to assess the prevalence rate and to define the characteristics of Peruvian patients. GC samples were prospectively collected from patients who underwent gastroscopy or surgical resection with no preoperative treatment at INEN between 2015 and 2017. Tumor tissue (T), proximal healthy tissue (P) and distal healthy tissue (D) samples were assessed for HP and EBV by quantitative PCR (qPCR) using specific primers. HP and EBV status were analyzed along with clinicopathologic parameters of the tumor. Kaplan-Meier estimation curves overall survival (OS) was applied. Comparison between qPCR detection and current standard methods of detection was also performed. All tests were two sided, and a p≤0.05 was considered statistically significant.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengAmerican Association for Cancer Researchinfo:eu-repo/semantics/openAccessHelicobacter pyloriGastric cancer-1Epstein-Barr virus-1https://purl.org/pe-repo/ocde/ford#3.02.21-1HP and EBVaGC in Peruvian patientsinfo:eu-repo/semantics/conferenceObjectreponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/1079oai:repositorio.concytec.gob.pe:20.500.12390/10792024-05-30 16:01:01.948http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="36bf96be-6d8f-442f-a6cf-067b11f9bba7"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>HP and EBVaGC in Peruvian patients</Title> <PublishedIn> <Publication> </Publication> </PublishedIn> <PublicationDate>2018</PublicationDate> <DOI>https://doi.org/10.1158/1538-7445.AM2018-4210</DOI> <ISI-Number>468819502407</ISI-Number> <Authors> <Author> <DisplayName>Lopez, CB</DisplayName> <Person id="rp03062" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Garcia, MC</DisplayName> <Person id="rp02711" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Altamirano, CAC</DisplayName> <Person id="rp03068" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Bolanos, LFB</DisplayName> <Person id="rp03066" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Leonardo, D</DisplayName> <Person id="rp03063" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Meza, EP</DisplayName> <Person id="rp03061" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Bernaola, VV</DisplayName> <Person id="rp03070" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Prado, JN</DisplayName> <Person id="rp03067" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Sifuentes, JRS</DisplayName> <Person id="rp03064" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Monsalve, LAB</DisplayName> <Person id="rp03065" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Sanchez, MACLR</DisplayName> <Person id="rp03071" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Dionisio, OM</DisplayName> <Person id="rp03069" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Passiuri, IC</DisplayName> <Person id="rp03072" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>American Association for Cancer Research</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>Helicobacter pylori</Keyword> <Keyword>Gastric cancer</Keyword> <Keyword>Epstein-Barr virus</Keyword> <Abstract>Gastric cancer (GC) is the second most common cancer and first leading cause of cancer-related deaths in Peru. Infection by Helicobacter pylori (HP) and Epstein-Barr virus (EBV) are accepted carcinogenic and infection is widely spread in the Peruvian population. The aims of this study were to evaluate HP and EBV-associated GC (EBVaCG), to assess the prevalence rate and to define the characteristics of Peruvian patients. GC samples were prospectively collected from patients who underwent gastroscopy or surgical resection with no preoperative treatment at INEN between 2015 and 2017. Tumor tissue (T), proximal healthy tissue (P) and distal healthy tissue (D) samples were assessed for HP and EBV by quantitative PCR (qPCR) using specific primers. HP and EBV status were analyzed along with clinicopathologic parameters of the tumor. Kaplan-Meier estimation curves overall survival (OS) was applied. Comparison between qPCR detection and current standard methods of detection was also performed. 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