Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects

Descripción del Articulo

This work was supported by grant CTQ2009-14629-C02-01 (Spain) and the Collaborative Research Project CSIC-CONCYTEC (Peru). W. R. M. thanks MAE-AECI (Spain) for a predoctoral fellowship. We also thank S. Carlin for language advice.
Detalles Bibliográficos
Autores: Reina, M, Ruiz-Mesia, W, Ruiz-Mesia, L, Martinez-Diaz, R, Gonzalez-Coloma, A
Formato: artículo
Fecha de Publicación:2011
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/1140
Enlace del recurso:https://hdl.handle.net/20.500.12390/1140
https://doi.org/10.5560/ZNC.2011.66c0225
Nivel de acceso:acceso abierto
Materia:Indole Alkaloids
Aspidosperma rigidum
Aspidosperma schultesii
https://purl.org/pe-repo/ocde/ford#1.06.01
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network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
title Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
spellingShingle Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
Reina, M
Indole Alkaloids
Aspidosperma rigidum
Aspidosperma schultesii
https://purl.org/pe-repo/ocde/ford#1.06.01
title_short Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
title_full Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
title_fullStr Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
title_full_unstemmed Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
title_sort Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
author Reina, M
author_facet Reina, M
Ruiz-Mesia, W
Ruiz-Mesia, L
Martinez-Diaz, R
Gonzalez-Coloma, A
author_role author
author2 Ruiz-Mesia, W
Ruiz-Mesia, L
Martinez-Diaz, R
Gonzalez-Coloma, A
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Reina, M
Ruiz-Mesia, W
Ruiz-Mesia, L
Martinez-Diaz, R
Gonzalez-Coloma, A
dc.subject.none.fl_str_mv Indole Alkaloids
topic Indole Alkaloids
Aspidosperma rigidum
Aspidosperma schultesii
https://purl.org/pe-repo/ocde/ford#1.06.01
dc.subject.es_PE.fl_str_mv Aspidosperma rigidum
Aspidosperma schultesii
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#1.06.01
description This work was supported by grant CTQ2009-14629-C02-01 (Spain) and the Collaborative Research Project CSIC-CONCYTEC (Peru). W. R. M. thanks MAE-AECI (Spain) for a predoctoral fellowship. We also thank S. Carlin for language advice.
publishDate 2011
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2011
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/1140
dc.identifier.doi.none.fl_str_mv https://doi.org/10.5560/ZNC.2011.66c0225
dc.identifier.isi.none.fl_str_mv 293804800005
url https://hdl.handle.net/20.500.12390/1140
https://doi.org/10.5560/ZNC.2011.66c0225
identifier_str_mv 293804800005
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Zeitschrift für Naturforschung C: A Journal of Biosciences
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/3.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/3.0/
dc.publisher.none.fl_str_mv Verlag der Zeitschrift fur Naturforschung
publisher.none.fl_str_mv Verlag der Zeitschrift fur Naturforschung
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844883131685928960
spelling Publicationrp03170500rp03226600rp03176500rp03225600rp03173500Reina, MRuiz-Mesia, WRuiz-Mesia, LMartinez-Diaz, RGonzalez-Coloma, A2024-05-30T23:13:38Z2024-05-30T23:13:38Z2011https://hdl.handle.net/20.500.12390/1140https://doi.org/10.5560/ZNC.2011.66c0225293804800005This work was supported by grant CTQ2009-14629-C02-01 (Spain) and the Collaborative Research Project CSIC-CONCYTEC (Peru). W. R. M. thanks MAE-AECI (Spain) for a predoctoral fellowship. We also thank S. Carlin for language advice.Five oxindole alkaloids, three plumerane-type alkaloids, subtype haplophitine, and one aspidospermatane-type alkaloid, subtype tubotaiwine, were isolated from the medicinal plants Aspidosperma rigidum and A. schultesii. One compound was identifi ed as the transoid conformer of 18-oxo-O-methylaspidoalbine which was not previously described. The antiparasitic activity of all compounds against Trypanosoma cruzi and Leishmania infantum and their non-specifi c cytotoxicity against mammalian cells were also determined.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengVerlag der Zeitschrift fur NaturforschungZeitschrift für Naturforschung C: A Journal of Biosciencesinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/3.0/Indole AlkaloidsAspidosperma rigidum-1Aspidosperma schultesii-1https://purl.org/pe-repo/ocde/ford#1.06.01-1Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effectsinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#20.500.12390/1140oai:repositorio.concytec.gob.pe:20.500.12390/11402024-05-30 15:23:44.909https://creativecommons.org/licenses/by-nc-nd/3.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="f99cb18d-0e73-43b8-9ef5-3cad77b8c1d1"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects</Title> <PublishedIn> <Publication> <Title>Zeitschrift für Naturforschung C: A Journal of Biosciences</Title> </Publication> </PublishedIn> <PublicationDate>2011</PublicationDate> <DOI>https://doi.org/10.5560/ZNC.2011.66c0225</DOI> <ISI-Number>293804800005</ISI-Number> <Authors> <Author> <DisplayName>Reina, M</DisplayName> <Person id="rp03170" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Ruiz-Mesia, W</DisplayName> <Person id="rp03226" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Ruiz-Mesia, L</DisplayName> <Person id="rp03176" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Martinez-Diaz, R</DisplayName> <Person id="rp03225" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gonzalez-Coloma, A</DisplayName> <Person id="rp03173" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Verlag der Zeitschrift fur Naturforschung</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by-nc-nd/3.0/</License> <Keyword>Indole Alkaloids</Keyword> <Keyword>Aspidosperma rigidum</Keyword> <Keyword>Aspidosperma schultesii</Keyword> <Abstract>Five oxindole alkaloids, three plumerane-type alkaloids, subtype haplophitine, and one aspidospermatane-type alkaloid, subtype tubotaiwine, were isolated from the medicinal plants Aspidosperma rigidum and A. schultesii. One compound was identifi ed as the transoid conformer of 18-oxo-O-methylaspidoalbine which was not previously described. The antiparasitic activity of all compounds against Trypanosoma cruzi and Leishmania infantum and their non-specifi c cytotoxicity against mammalian cells were also determined.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
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Indole Alkaloids from Aspidosperma rigidum and A. schultesii and their Antiparasitic Effects
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