Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate

Descripción del Articulo

PROCOM 2009
Detalles Bibliográficos
Autores: Leiva, KP, Rubio, J, Peralta, F, Gonzales, GF
Formato: artículo
Fecha de Publicación:2011
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/1245
Enlace del recurso:https://hdl.handle.net/20.500.12390/1245
https://doi.org/10.3109/15376516.2011.555789
Nivel de acceso:acceso abierto
Materia:producción diaria de esperma
Actividad antioxidante
acetato de plomo
extracto etanólico de granada
número de espermatozoides
espermatogénesis
https://purl.org/pe-repo/ocde/ford#1.06.08
id CONC_17fb22553aeccdd06d91ec21affd4c66
oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/1245
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
title Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
spellingShingle Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
Leiva, KP
producción diaria de esperma
Actividad antioxidante
acetato de plomo
extracto etanólico de granada
número de espermatozoides
espermatogénesis
https://purl.org/pe-repo/ocde/ford#1.06.08
title_short Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
title_full Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
title_fullStr Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
title_full_unstemmed Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
title_sort Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
author Leiva, KP
author_facet Leiva, KP
Rubio, J
Peralta, F
Gonzales, GF
author_role author
author2 Rubio, J
Peralta, F
Gonzales, GF
author2_role author
author
author
dc.contributor.author.fl_str_mv Leiva, KP
Rubio, J
Peralta, F
Gonzales, GF
dc.subject.none.fl_str_mv producción diaria de esperma
topic producción diaria de esperma
Actividad antioxidante
acetato de plomo
extracto etanólico de granada
número de espermatozoides
espermatogénesis
https://purl.org/pe-repo/ocde/ford#1.06.08
dc.subject.es_PE.fl_str_mv Actividad antioxidante
acetato de plomo
extracto etanólico de granada
número de espermatozoides
espermatogénesis
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#1.06.08
description PROCOM 2009
publishDate 2011
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2011
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/1245
dc.identifier.doi.none.fl_str_mv https://doi.org/10.3109/15376516.2011.555789
dc.identifier.isi.none.fl_str_mv 291392400008
url https://hdl.handle.net/20.500.12390/1245
https://doi.org/10.3109/15376516.2011.555789
identifier_str_mv 291392400008
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Toxicology Mechanisms and Methods
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Taylor & Francis Online
publisher.none.fl_str_mv Taylor & Francis Online
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844883036410216448
spelling Publicationrp03596600rp01560500rp03106500rp00575500Leiva, KPRubio, JPeralta, FGonzales, GF2024-05-30T23:13:38Z2024-05-30T23:13:38Z2011https://hdl.handle.net/20.500.12390/1245https://doi.org/10.3109/15376516.2011.555789291392400008PROCOM 2009The present study was designed to determine whether the treatment with an ethanolic extract of pomegranate (EEP) (Punica granatum) can be useful for the treatment of the deleterious effect of lead acetate (LA) administration on sperm production in rats. The effects of EEP were compared with those of ascorbic acid (AA) that is a strong antioxidant and has been shown to reverse lead-induced damage on the reproductive system. The rats were divided into five different groups: those received distilled water (control group), LA, LA with EEP, LA with AA, and EEP alone, respectively. LA administration inhibited spermatogenesis by reducing the length of the stages related to spermiation (VII and VIII) and onset of mitosis (IX-XI). LA-treated rats also showed a reduction in epididymal sperm number and daily sperm production (DSP). Administration of EEP or AA resulted in longer VIII and IX-XI stages when compared with LA-treated rats. Moreover, EEP and AA administration reduced the deleterious effect of LA on DSP and epididymal sperm number. EEP showed an antioxidant activity similar to that of AA. EEP prevented LA-induced spermatogenic disruption in rats and its antioxidant activity could explain its capacity to reverse the damage produced by LA on spermatogenesis.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengTaylor & Francis OnlineToxicology Mechanisms and Methodsinfo:eu-repo/semantics/openAccessproducción diaria de espermaActividad antioxidante-1acetato de plomo-1extracto etanólico de granada-1número de espermatozoides-1espermatogénesis-1https://purl.org/pe-repo/ocde/ford#1.06.08-1Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetateinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/1245oai:repositorio.concytec.gob.pe:20.500.12390/12452024-05-30 16:02:03.961http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="d880d882-8b1e-4fe6-a75f-165fda398552"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate</Title> <PublishedIn> <Publication> <Title>Toxicology Mechanisms and Methods</Title> </Publication> </PublishedIn> <PublicationDate>2011</PublicationDate> <DOI>https://doi.org/10.3109/15376516.2011.555789</DOI> <ISI-Number>291392400008</ISI-Number> <Authors> <Author> <DisplayName>Leiva, KP</DisplayName> <Person id="rp03596" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Rubio, J</DisplayName> <Person id="rp01560" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Peralta, F</DisplayName> <Person id="rp03106" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gonzales, GF</DisplayName> <Person id="rp00575" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Taylor &amp; Francis Online</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>producción diaria de esperma</Keyword> <Keyword>Actividad antioxidante</Keyword> <Keyword>acetato de plomo</Keyword> <Keyword>extracto etanólico de granada</Keyword> <Keyword>número de espermatozoides</Keyword> <Keyword>espermatogénesis</Keyword> <Abstract>The present study was designed to determine whether the treatment with an ethanolic extract of pomegranate (EEP) (Punica granatum) can be useful for the treatment of the deleterious effect of lead acetate (LA) administration on sperm production in rats. The effects of EEP were compared with those of ascorbic acid (AA) that is a strong antioxidant and has been shown to reverse lead-induced damage on the reproductive system. The rats were divided into five different groups: those received distilled water (control group), LA, LA with EEP, LA with AA, and EEP alone, respectively. LA administration inhibited spermatogenesis by reducing the length of the stages related to spermiation (VII and VIII) and onset of mitosis (IX-XI). LA-treated rats also showed a reduction in epididymal sperm number and daily sperm production (DSP). Administration of EEP or AA resulted in longer VIII and IX-XI stages when compared with LA-treated rats. Moreover, EEP and AA administration reduced the deleterious effect of LA on DSP and epididymal sperm number. EEP showed an antioxidant activity similar to that of AA. EEP prevented LA-induced spermatogenic disruption in rats and its antioxidant activity could explain its capacity to reverse the damage produced by LA on spermatogenesis.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.394457
Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares