Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung

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We gratefully acknowledge financial support by CONCYTEC Peru within the program Programa nacional de innovación para la competitividad y productividad (PNICP, 361-PNICP-PIBA-2014) as well as travel support by the Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (...

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Detalles Bibliográficos
Autores: Caucha L.J., Frei S., Rubio O.
Formato: artículo
Fecha de Publicación:2018
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/852
Enlace del recurso:https://hdl.handle.net/20.500.12390/852
https://doi.org/10.1007/s40314-018-0692-5
Nivel de acceso:acceso abierto
Materia:Método arbitrario Lagrangiano-Euleriano (ALE)
Dinámica de gases alveolares
Estabilización de presión anisotrópica
Condiciones de contorno artificiales
Estabilización de proyección local
Estabilización de penalti interior
https://purl.org/pe-repo/ocde/ford#1.02.01
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oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/852
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
title Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
spellingShingle Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
Caucha L.J.
Método arbitrario Lagrangiano-Euleriano (ALE)
Dinámica de gases alveolares
Dinámica de gases alveolares
Estabilización de presión anisotrópica
Estabilización de presión anisotrópica
Condiciones de contorno artificiales
Condiciones de contorno artificiales
Estabilización de proyección local
Estabilización de penalti interior
https://purl.org/pe-repo/ocde/ford#1.02.01
title_short Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
title_full Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
title_fullStr Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
title_full_unstemmed Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
title_sort Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
author Caucha L.J.
author_facet Caucha L.J.
Frei S.
Rubio O.
author_role author
author2 Frei S.
Rubio O.
author2_role author
author
dc.contributor.author.fl_str_mv Caucha L.J.
Frei S.
Rubio O.
dc.subject.none.fl_str_mv Método arbitrario Lagrangiano-Euleriano (ALE)
topic Método arbitrario Lagrangiano-Euleriano (ALE)
Dinámica de gases alveolares
Dinámica de gases alveolares
Estabilización de presión anisotrópica
Estabilización de presión anisotrópica
Condiciones de contorno artificiales
Condiciones de contorno artificiales
Estabilización de proyección local
Estabilización de penalti interior
https://purl.org/pe-repo/ocde/ford#1.02.01
dc.subject.es_PE.fl_str_mv Dinámica de gases alveolares
Dinámica de gases alveolares
Estabilización de presión anisotrópica
Estabilización de presión anisotrópica
Condiciones de contorno artificiales
Condiciones de contorno artificiales
Estabilización de proyección local
Estabilización de penalti interior
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#1.02.01
description We gratefully acknowledge financial support by CONCYTEC Peru within the program Programa nacional de innovación para la competitividad y productividad (PNICP, 361-PNICP-PIBA-2014) as well as travel support by the Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (HGS MathComp). The second author was supported by the DFG Research Scholarship FR3935/1-1.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/852
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1007/s40314-018-0692-5
dc.identifier.scopus.none.fl_str_mv 2-s2.0-85058165129
url https://hdl.handle.net/20.500.12390/852
https://doi.org/10.1007/s40314-018-0692-5
identifier_str_mv 2-s2.0-85058165129
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Computational and Applied Mathematics
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Science and Business Media, LLC
publisher.none.fl_str_mv Springer Science and Business Media, LLC
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1870084282475610112
spelling Publicationrp02203600rp02204600rp02202600Caucha L.J.Frei S.Rubio O.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2018https://hdl.handle.net/20.500.12390/852https://doi.org/10.1007/s40314-018-0692-52-s2.0-85058165129We gratefully acknowledge financial support by CONCYTEC Peru within the program Programa nacional de innovación para la competitividad y productividad (PNICP, 361-PNICP-PIBA-2014) as well as travel support by the Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (HGS MathComp). The second author was supported by the DFG Research Scholarship FR3935/1-1.In this article, we present a numerical framework based on continuum models for the fluid dynamics and the CO2 gas distribution in the alveolar sacs of the human lung during expiration and inspiration, including the gas exchange to the cardiovascular system. We include the expansion and contraction of the geometry by means of the Arbitrary Lagrangian–Eulerian (ALE) method. For discretisation, we use equal-order finite elements in combination with pressure-stabilisation techniques based on local projections or interior penalties. We derive formulations for both techniques that are suitable on arbitrarily anisotropic meshes. These formulations are novel within the ALE method. Moreover, we investigate the effect of different boundary conditions, that vary between inspiration and expiration. We present numerical results on a simplified two-dimensional alveolar sac geometry and investigate the influence of the pressure stabilisations as well as the boundary conditions.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengSpringer Science and Business Media, LLCComputational and Applied Mathematicsinfo:eu-repo/semantics/openAccessMétodo arbitrario Lagrangiano-Euleriano (ALE)Dinámica de gases alveolares-1Dinámica de gases alveolares-1Estabilización de presión anisotrópica-1Estabilización de presión anisotrópica-1Condiciones de contorno artificiales-1Condiciones de contorno artificiales-1Estabilización de proyección local-1Estabilización de penalti interior-1https://purl.org/pe-repo/ocde/ford#1.02.01-1Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lunginfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/852oai:repositorio.concytec.gob.pe:20.500.12390/8522024-05-30 15:59:30.586http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="1d94f9e9-8b49-43d4-9aa8-b5f3fead3477"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung</Title> <PublishedIn> <Publication> <Title>Computational and Applied Mathematics</Title> </Publication> </PublishedIn> <PublicationDate>2018</PublicationDate> <DOI>https://doi.org/10.1007/s40314-018-0692-5</DOI> <SCP-Number>2-s2.0-85058165129</SCP-Number> <Authors> <Author> <DisplayName>Caucha L.J.</DisplayName> <Person id="rp02203" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Frei S.</DisplayName> <Person id="rp02204" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Rubio O.</DisplayName> <Person id="rp02202" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Springer Science and Business Media, LLC</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>Método arbitrario Lagrangiano-Euleriano (ALE)</Keyword> <Keyword>Dinámica de gases alveolares</Keyword> <Keyword>Dinámica de gases alveolares</Keyword> <Keyword>Estabilización de presión anisotrópica</Keyword> <Keyword>Estabilización de presión anisotrópica</Keyword> <Keyword>Condiciones de contorno artificiales</Keyword> <Keyword>Condiciones de contorno artificiales</Keyword> <Keyword>Estabilización de proyección local</Keyword> <Keyword>Estabilización de penalti interior</Keyword> <Abstract>In this article, we present a numerical framework based on continuum models for the fluid dynamics and the CO2 gas distribution in the alveolar sacs of the human lung during expiration and inspiration, including the gas exchange to the cardiovascular system. We include the expansion and contraction of the geometry by means of the Arbitrary Lagrangian–Eulerian (ALE) method. For discretisation, we use equal-order finite elements in combination with pressure-stabilisation techniques based on local projections or interior penalties. We derive formulations for both techniques that are suitable on arbitrarily anisotropic meshes. These formulations are novel within the ALE method. Moreover, we investigate the effect of different boundary conditions, that vary between inspiration and expiration. We present numerical results on a simplified two-dimensional alveolar sac geometry and investigate the influence of the pressure stabilisations as well as the boundary conditions.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.411838
Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
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