Objective. To assess the protective effect of the vaccine against SARS-CoV-2 upon hospitalizations due to COVID-19 during the fourth epidemic wave in Queretaro, Mexico. Methods. This investigation was designed as a retrospective cohort study in patients with COVID-19 during the fourth wave of the epidemic (December 19th, 2021, to January 9th, 2022). The exposed group consisted in those subjects who had received a vaccine against COVID-19 (genetically modified adenovirus vaccine and messenger ribonucleic acid vaccine); and the non-exposed group consisted in those people who were not vaccinated. Diagnosis of COVID-19 was made with a rapid antigenic test in oropharyngeal exudate, and the test was performed between the first and fifth day after the onset of symptoms. All patients who came to healthcare facilities because of symptoms, with a positive test and having received two doses of the ...

Objetivo. Determinar la vacunación como factor protector para hospitalización en paciente con COVID-19 en la cuarta ola de la pandemia. Métodos. Diseño de cohorte retrospectiva en pacientes con COVID-19 durante la cuarta ola (1 enero a 9 febrero de 2022). Grupos expuestos, antecedente de vacuna anti COVID-19 (vacuna de adenovirus modificado genéticamente y vacuna de ácido ribonucleico mensajero), grupo no expuestos, no vacuna. Tamaño de muestra todos los casos del periodo, grupo expuesto (vacuna de adenovirus modificados genéticamente, n=41; vacuna de ácido ribonucleico mensajero, n=105; y grupo no expuesto, n=263. Análisis estadístico, chi cuadrada, riesgo relativo, regresión logística múltiple y cálculo de probabilidad de ocurrencia del evento. Resultados. En una mujer entre 50 y 59 años que no tiene enfermedad crónica degenerativa y que recibió vacuna de adenovirus m...

Objective: To determine the association between frailty syndrome and family functioning among older adults with diabetic retinopathy. Materials and methods: An analytical and cross-sectional study conducted among patients diagnosed with diabetic retinopathy. The ophthalmology department diagnosed diabetic retinopathy through pupil dilation, using tetracaine and an ophthalmoscope. Three groups were determined using the FRAIL questionnaire: frail, prefrail and nonfrail; the sample sizes were 39, 64 and 76, respectively, matched by age. The study variables included age, sex, education, marital status and occupation. Additionally, the time since the diagnosis of diabetic retinopathy was measured. Furthermore, the type of family was determined according to Huerta’s classification, which identifies nuclear family, extended family, composite extended family, single-parent family and blended f...

Objective: To identify the association between obesity and depression symptoms in adolescents attended in a family health center. Materials and Methods: An observational, cross-sectional, comparative study of Mexican adolescents aged 10 to 19 years integrated two comparison groups, adolescents with obesity and without obesity. The sample size was 97 adolescents per group, non-probabilistic sampling per quota was used. Depression was evaluated with the revised version of the Center for Epidemiological Studies (CESD-R) Depression Scale. The statistical analysis included averages, percentages, standard deviations, chi square test, odds ratio (OR), and confidence intervals for OR. Results: In the group of adolescents with obesity 48,5% presented depressive symptoms and in the group of adolescents without obesity 33% also presented depressive symptoms (p=0,02), RM was 1,90 (95%CI; 1,06-3,41)....

Objective: To identify the association between obesity and depression symptoms in adolescents attended in a family health center. Materials and Methods: An observational, cross-sectional, comparative study of Mexican adolescents aged 10 to 19 years integrated two comparison groups, adolescents with obesity and without obesity. The sample size was 97 adolescents per group, non-probabilistic sampling per quota was used. Depression was evaluated with the revised version of the Center for Epidemiological Studies (CESD-R) Depression Scale. The statistical analysis included averages, percentages, standard deviations, chi square test, odds ratio (OR), and confidence intervals for OR. Results: In the group of adolescents with obesity 48,5% presented depressive symptoms and in the group of adolescents without obesity 33% also presented depressive symptoms (p=0,02), RM was 1,90 (95%CI; 1,06-3,41)....

Objective: To identify the factors associated with adherence to drug therapy among patients with type 2 diabetes mellitus without hypertension. Materials and methods: A cross-sectional, analytical study conducted with patients with type 2 diabetes mellituswithout hypertension, divided into an adherent group (n = 145) and a non-adherent group (n = 49), determined by the 4-item Morisky Medication Adherence Scale (MMAS-4). The associated factors were sex, cohabitation, schooling, occupation, age in 10-year groups and diabetes progression time grouped in less than 1 year, from 1 to 5 years, from6 to 10 years and more than 10 years. The statistical analysis plan included the chi-square test. Results: The factors associated with adherence to drug therapy were identified as sex (p = 0.045), cohabitation (p = 0.045), age (p = 0.001) and disease progression time (p = 0.001). Schooling was not ide...

Objective: To determine the effectiveness of an educational program for the control of glycatedhemoglobin (HbA1c) in patients with diabetes. Materials and methods: A before-and-after cohortstudy was conducted in patients with diabetes. Participants received an educational interventionconsisting of individualized monthly medical care by a family doctor and educational sessions bythe nursing staff over a six-month period. Follow-up was performed with a multidisciplinary team,with timely referrals to secondary care in ophthalmology, endocrinology and internal medicine,based on the specific needs of each patient. To ensure the temporal effect of the intervention inrelation to the impact on HbA1c, it was measured before and after the educational interventionfollowing the 2020 American Diabetes Association (ADA) Standards of Medical Care in Diabetes.Patients with normal HbA1c levels were exclu...