Objective. To evaluate the degree of incomplete revascularization in patients with multiarterial coronary artery disease who underwent percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) using the Syntax revascularization index (SRI) and its relationship to major cardiovascular events during follow-up. Materials and Methods. Observational, retrospective study with 4-year follow-up of patients with multiarterial coronary artery disease who underwent surgical or percutaneous coronary revascularization, in whom the baseline Syntax score (SSb) and the residualSyntax score (SSr) were calculated. The Syntax Revascularization Index (SRI) was determined withthe following formula: SRI = (1- [SSr/SSb]) x 100, and major cardiovascular events at 4-year follow-up were compared. Results. Two hundred patients (100 in each group) were evaluated. Mean SSr in group 1 was 83.2...

Objetivo. Evaluar el grado de revascularización incompleta en pacientes con enfermedad coronaria multiarterial sometidos a intervención coronaria percutánea (ICP) o cirugía de baipás coronario (CABG) mediante el índice de revascularización SYNTAX (IRS) y su relación con eventos cardiovasculares mayores en el seguimiento. Materiales y métodos. Estudio observacional, retrospectivo con seguimiento a 4 años de pacientes con enfermedad coronaria multiarterial, sometidos a revascularización coronaria quirúrgica o percutánea, en quienes se calculó el score SYNTAX basal (SSb) y el score SYNTAX residual (SSr). Se determinó el índice de revascularización SYNTAX (IRS) con la siguiente fórmula: IRS = (1– [SSr/SSb]) x 100 y se compararon los eventos cardiovasculares mayores en el seguimiento a 4 años. Resultados. Doscientos pacientes (cien en cada grupo) fueron evaluados. El IRS ...

Objective. To evaluate the degree of incomplete revascularization in patients with multiarterial coronary artery disease who underwent percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) using the Syntax revascularization index (SRI) and its relationship to major cardiovascular events during follow-up. Materials and Methods. Observational, retrospective study with 4-year follow-up of patients with multiarterial coronary artery disease who underwent surgical or percutaneous coronary revascularization, in whom the baseline Syntax score (SSb) and the residualSyntax score (SSr) were calculated. The Syntax Revascularization Index (SRI) was determined withthe following formula: SRI = (1- [SSr/SSb]) x 100, and major cardiovascular events at 4-year follow-up were compared. Results. Two hundred patients (100 in each group) were evaluated. Mean SSr in group 1 was 83.2...

Objectives. To analyze the scientific production framed in the National Research Agenda 2011-2014. Design. Bibliometric research using SCOPUS, LILACS and LIPECS databases. Setting National Health Institute, Lima, Peru. Unit of analysis. Original article with at least one researcher with a Peruvian institution affiliation or whose study population or part of it, came from Peru and framed on any issue of national research agendas. Main outcome measures. Bibliometric indicators of production. Results. Out of the 882 publications retrieved, 215 (24.4%) were admitted to the analysis. The national research agendas with more scientific production were tuberculosis and STD-HIV/AIDS that included 78 and 59 articles respectively. The most common language of publication was English (69.8%). The articles were published in 90 scientific journals. Peruvian institutions with the highest number of signa...

Objective: to establish the ratios of the copy number variations and regions of homozygosity through chromosomal microarray analysis (CMA) in children with neurodevelopmental disorders: development delay (DD), intellectual disability (ID), and/or autistic spectrum disorder (ASD), malformative syndrome (MS) and idiopathic short stature (ISS). Materials and methods: we evaluated 367 Peruvian children diagnosed clinically with ID, DD, ASD, ISS and MS to whom performed chromosomal microarray analysis in peripheral blood (750K CGH + SNP), between the years 2016-2018. Results: patients' age fluctuated between 4.8 months and 18 years old, with an average of 5.6 years old. The most frequent diagnoses were development delay (48%) and intellectual disability (30%). Abnormal results (pathogenic variants, likely pathogenic variants, uniparental disomies and loss of heterozygosity> 2.5%) were repo...

Objective: to establish the ratios of the copy number variations and regions of homozygosity through chromosomal microarray analysis (CMA) in children with neurodevelopmental disorders: development delay (DD), intellectual disability (ID), and/or autistic spectrum disorder (ASD), malformative syndrome (MS) and idiopathic short stature (ISS). Materials and methods: we evaluated 367 Peruvian children diagnosed clinically with ID, DD, ASD, ISS and MS to whom performed chromosomal microarray analysis in peripheral blood (750K CGH + SNP), between the years 2016-2018. Results: patients' age fluctuated between 4.8 months and 18 years old, with an average of 5.6 years old. The most frequent diagnoses were development delay (48%) and intellectual disability (30%). Abnormal results (pathogenic variants, likely pathogenic variants, uniparental disomies and loss of heterozygosity> 2.5%) were repo...