Objective: To determine if anemia is a predictor of poor neurological functional status in the short term in adult patients hospitalized for acute ischemic cerebrovascular disease. Materials and methods: A prospective analytical observational study in which 96 patients hospitalized for acute ischemic cerebrovascular disease were followed up in Hospital Regional Docente de Trujillo (HRDT) in the period 2017-2018. It was distributed to patients according to the presence or absence of anemia and functional status was recorded (using the modified Rankin scale) on the first and 14th day of admission, as well as sociodemographic, clinical and laboratory variables. Results: The average age of patients was 73 years. The prevalence of anemia at admission and poor functional status at 14 days was 41.6% and 66.6%, respectively. It was found that anemia increased the risk of presenting poor function...

Introduccion: El síndrome hemofagocítico o linfohistiocitosis hemofagocítica (HLH) es una de las enfermedades más raras en pediatría debido a su poca prevalencia descrita; sobretodo, en países en vías de desarrollo como en Latinoamerica. Se define a la HLH como la activacion desregulada de linfocitos T y citoquinas lo cual produce gran inflamacion ocasionando signos y síntomas sistémicos como fiebre, visceromegalia, elevación de reactantes de fase aguda, citopenias, entre otros. El tratamiento consiste en revertir la respuesta inmune desenfrenada. Para ello, es necesario administrar agentes inmunosupresores como dexametasona, etopósido y ciclosporina A según los protocolos de 1994 y 2004; sin embargo, aún sigue siendo controversial. En los últimos años, se describe en Latinoamérica una mortalidad del 55% con una tasa de supervivencia de 38% al año del diagnóstico, por e...

Objective: To estimate the role of age as a predictor of COVID-19 severity in pediatric patients hospitalized with a COVID-19 diagnosis at a reference hospital in Peru. Materials and methods: A retrospective cohort study was conducted, including pediatric patients from one month old to less than 14 years of age, hospitalized between May 2020 and December 31, 2021, at the Edgardo Rebagliati-Martins National Hospital. The exposure variable was age, categorized in six-month intervals. The outcome variable was the severity of COVID-19, determined according to the severity criteria established in the EsSalud Clinical Practice Guidelines for the management of COVID-19 in pediatrics. Crude and adjusted relative risks (RR) were estimated, with their respective 95% confidence intervals (95% CI). Results: Three-hundred and thirty-one patients were analyzed, their median age was 94 months (7,8 year...