Over the last decades, there has been a clear tendency in couples planning to have children later in life. Better educational and career opportunities and broad availability of contraception have been some of the contributing factors in couples postponing the beginning of a family. Advanced maternal age (AMA) is currently considered the main risk factor for chromosome aneuploidies, but there is no exact number as to the probability of actually producing aneuploid embryos or a mayor reason for this to happen. The object of this review is to address the recent findings and to near down the probability of actually producing aneuploidy embryos in AMA women. Also we will try to elucidate the actual reason as to why this is happening and how it is related to the age of the mother. We hope these findings will help couples that are thinking about starting a family and couples that are starting o...

Over the last decades, there has been a clear tendency in couples planning to have children later in life. Better educational and career opportunities and broad availability of contraception have been some of the contributing factors in couples postponing the beginning of a family. Advanced maternal age (AMA) is currently considered the main risk factor for chromosome aneuploidies, but there is no exact number as to the probability of actually producing aneuploid embryos or a mayor reason for this to happen. The object of this review is to address the recent findings and to near down the probability of actually producing aneuploidy embryos in AMA women. Also we will try to elucidate the actual reason as to why this is happening and how it is related to the age of the mother. We hope these findings will help couples that are thinking about starting a family and couples that are starting o...

Background: Preimplantation genetic screening (PGS) using comparative genomics hybridization  (aCGH) and single nucleotide polymorphism (SNP) technology has become a useful tool in assisted reproduction by improving clinical outcomes. Both techniques identify aneuploidies and chromosomal rearrangement. However, SNPs with Parental Support (Natera Inc.) give extra information of the aneuploidy origin either from the sperm or the oocyte. Objectives: To determine single aneuplodies rate in human embryos obtained by assisted reproduction using single nucleotide polymorphism microarray. Design: Retrospective study. Setting: Grupo PRANOR, Sede Monterrico, and Genomics Peru, Lima, Peru. Biologic material: Human embryos. Interventions: From 2011 to 2013, 105 patients underwent IVF/ICSI with SNPs and Parental Support. In total, 429 embryos were analyzed and records were reviewed. Main outcome mea...

Background: Preimplantation genetic screening (PGS) using comparative genomics hybridization  (aCGH) and single nucleotide polymorphism (SNP) technology has become a useful tool in assisted reproduction by improving clinical outcomes. Both techniques identify aneuploidies and chromosomal rearrangement. However, SNPs with Parental Support (Natera Inc.) give extra information of the aneuploidy origin either from the sperm or the oocyte. Objectives: To determine single aneuplodies rate in human embryos obtained by assisted reproduction using single nucleotide polymorphism microarray. Design: Retrospective study. Setting: Grupo PRANOR, Sede Monterrico, and Genomics Peru, Lima, Peru. Biologic material: Human embryos. Interventions: From 2011 to 2013, 105 patients underwent IVF/ICSI with SNPs and Parental Support. In total, 429 embryos were analyzed and records were reviewed. Main outcome mea...