1
artículo
Publicado 2014
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Enlace
Background: Preimplantation genetic screening (PGS) using comparative genomics hybridization (aCGH) and single nucleotide polymorphism (SNP) technology has become a useful tool in assisted reproduction by improving clinical outcomes. Both techniques identify aneuploidies and chromosomal rearrangement. However, SNPs with Parental Support (Natera Inc.) give extra information of the aneuploidy origin either from the sperm or the oocyte. Objectives: To determine single aneuplodies rate in human embryos obtained by assisted reproduction using single nucleotide polymorphism microarray. Design: Retrospective study. Setting: Grupo PRANOR, Sede Monterrico, and Genomics Peru, Lima, Peru. Biologic material: Human embryos. Interventions: From 2011 to 2013, 105 patients underwent IVF/ICSI with SNPs and Parental Support. In total, 429 embryos were analyzed and records were reviewed. Main outcome mea...
2
artículo
Publicado 2014
Enlace
Enlace
Background: Preimplantation genetic screening (PGS) using comparative genomics hybridization (aCGH) and single nucleotide polymorphism (SNP) technology has become a useful tool in assisted reproduction by improving clinical outcomes. Both techniques identify aneuploidies and chromosomal rearrangement. However, SNPs with Parental Support (Natera Inc.) give extra information of the aneuploidy origin either from the sperm or the oocyte. Objectives: To determine single aneuplodies rate in human embryos obtained by assisted reproduction using single nucleotide polymorphism microarray. Design: Retrospective study. Setting: Grupo PRANOR, Sede Monterrico, and Genomics Peru, Lima, Peru. Biologic material: Human embryos. Interventions: From 2011 to 2013, 105 patients underwent IVF/ICSI with SNPs and Parental Support. In total, 429 embryos were analyzed and records were reviewed. Main outcome mea...