OBJETIVE: To determine whether there is a difference in the efficacy and tolerance of sublingual misoprostol and oxytocin intramuscularly in the prevention of postpartum hemorrhage. DESIGN: randomized clinical trial conducted in the "Sergio E. Benales" de Lima Hospital, during the period from January to October 2003. MATERIALS AND METHODS: The sample consisted of 136 women in labor divided into two groups: group 1, 68 patients were administered 2OOμg misoprostol sublingually and group II, 68 patients were injected with 10 IU oxytocin intramuscularly immediately after expulsion. RESULTS: In the misoprostol group, the average birth and postpartum bleeding time was 18 min 2 sec 486.6 mL; respectively, while the oxytocin 1O min 53 s and 317.12 mL on average, respectively, with statistically significant differences. significant decrease in the average hematocrit value was found before and a...

OBJETIVE: To determine whether there is a difference in the efficacy and tolerance of sublingual misoprostol and oxytocin intramuscularly in the prevention of postpartum hemorrhage. DESIGN: randomized clinical trial conducted in the "Sergio E. Benales" de Lima Hospital, during the period from January to October 2003. MATERIALS AND METHODS: The sample consisted of 136 women in labor divided into two groups: group 1, 68 patients were administered 2OOμg misoprostol sublingually and group II, 68 patients were injected with 10 IU oxytocin intramuscularly immediately after expulsion. RESULTS: In the misoprostol group, the average birth and postpartum bleeding time was 18 min 2 sec 486.6 mL; respectively, while the oxytocin 1O min 53 s and 317.12 mL on average, respectively, with statistically significant differences. significant decrease in the average hematocrit value was found before and a...