In the year 2022 according to the United Nations, the world population is three times larger than the twentieth century, which affects the demand for land and consequently the cost per m2 increases. Likewise, it requires occupants to choose to build high-rise buildings to maximize the area acquired, consequently most structures require huge shear walls that increase the cost in steel, and in turn reduce the profitability of real estate for lack of aesthetic spaces on the floors. Now, recent architectural models do not allow regular structures, consequently, different irregularities occur. The present work develops the influence of vertical geometric irregularity in high-rise buildings with base isolation system, by which the researchers, modellers and designers, carried out the analysis of a regular pattern model (MPAT) based on shear walls, columns and beams against 12 different models,...