A 38-year-old man from Lima, with a history of HIV for three years in treatment, presented with a sensation of thermal elevation, nocturnal diaphoresis and productive cough with whitish expectoration; he also had a pulsating bitemporal headache and, one week before admission, he presented shortness of breath associated with sore throat, dysphonia and oppressive chest pain of intensity 6/10. Due to persistence of symptoms, he went to the Emergency Department, where the chest X-ray showed a mediastinal mass, so it was decided to hospitalize him. Chest TEM showed a left mediastinal mass, with multiple cervical and mediastinal adenopathies; and abdominal TEM showed a mass in the aortic bifurcation and multiple pararaortic and inguinal nodes. Inguinal node biopsyshowed histology compatible with Castleman’s disease. Chemotherapy was started, with favorable evolution and improvement of sympto...

The case of a 20-year-old male patient is presented, with an illness of one week characterized by asthenia, hyporexia, nausea, vomiting, neck stiffness, intermittent headache of intensity 9/10, fever quantified at 38.5. °C, scant dry cough, weight loss and left hemiparesis without loss of consciousness. Serological tests, including HIV, were negative. The spinal fluid showed pleocytosis with a predominance of mononuclear cells, hyperproteinorrachia and hypoglycorrhachia, with a positive GeneXpert MTB/RIF test for M. tuberculosis resistant to rifampicin, in addition to a positive sputum smear for the same germ. The images showed a miliary pattern and vascular compromise (bilateral hypodensities at the level of the basal ganglia and internal capsule). He was treated as multidrug-resistant systemic tuberculosis with a favorable outcome.