This paper is a prospective evaluation of 59 patients with facial melanosis treatment they received as bromocriptine 5 mg / day for 6 months. After treatment of 51 patients improved and in 9 patients Melanosis melanosis persisted. In this study group 38 patients with hyperprolactinemia and after six months was found in 7 patients and 31 Hyperprolactinaemia persisted and were Normoprolactenemicas. Also in the group of 30 patients they had Galactorrea Melanosis and the end of treatment only 1 patient still had Galactorrea, while the remaining 37 were no longer Galactorrea. The fact that a dopamine fix on the one hand and on the other Melanosis hyperprolactinemia and galactorrhea, indicating that secretion of prolactin and alpha-MSH is under inhibitory control by dopamine would be the PIF and physiological MIF.

This paper is a prospective evaluation of 59 patients with facial melanosis treatment they received as bromocriptine 5 mg / day for 6 months. After treatment of 51 patients improved and in 9 patients Melanosis melanosis persisted. In this study group 38 patients with hyperprolactinemia and after six months was found in 7 patients and 31 Hyperprolactinaemia persisted and were Normoprolactenemicas. Also in the group of 30 patients they had Galactorrea Melanosis and the end of treatment only 1 patient still had Galactorrea, while the remaining 37 were no longer Galactorrea. The fact that a dopamine fix on the one hand and on the other Melanosis hyperprolactinemia and galactorrhea, indicating that secretion of prolactin and alpha-MSH is under inhibitory control by dopamine would be the PIF and physiological MIF.