This publication will discuss a review of the research and the opinions of scientific groups that have been most devoted to the study of the actions of estrogen on non-sexual organs. This study is necessary because, with the increasing use of these hormones as contraceptives and replacement therapies, it is essential to know the best possible advantages and disadvantages of such treatment can lead to systems which are not directed.

This publication will discuss a review of the research and the opinions of scientific groups that have been most devoted to the study of the actions of estrogen on non-sexual organs. This study is necessary because, with the increasing use of these hormones as contraceptives and replacement therapies, it is essential to know the best possible advantages and disadvantages of such treatment can lead to systems which are not directed.

This paper is a prospective evaluation of 59 patients with facial melanosis treatment they received as bromocriptine 5 mg / day for 6 months. After treatment of 51 patients improved and in 9 patients Melanosis melanosis persisted. In this study group 38 patients with hyperprolactinemia and after six months was found in 7 patients and 31 Hyperprolactinaemia persisted and were Normoprolactenemicas. Also in the group of 30 patients they had Galactorrea Melanosis and the end of treatment only 1 patient still had Galactorrea, while the remaining 37 were no longer Galactorrea. The fact that a dopamine fix on the one hand and on the other Melanosis hyperprolactinemia and galactorrhea, indicating that secretion of prolactin and alpha-MSH is under inhibitory control by dopamine would be the PIF and physiological MIF.

This paper is a prospective evaluation of 59 patients with facial melanosis treatment they received as bromocriptine 5 mg / day for 6 months. After treatment of 51 patients improved and in 9 patients Melanosis melanosis persisted. In this study group 38 patients with hyperprolactinemia and after six months was found in 7 patients and 31 Hyperprolactinaemia persisted and were Normoprolactenemicas. Also in the group of 30 patients they had Galactorrea Melanosis and the end of treatment only 1 patient still had Galactorrea, while the remaining 37 were no longer Galactorrea. The fact that a dopamine fix on the one hand and on the other Melanosis hyperprolactinemia and galactorrhea, indicating that secretion of prolactin and alpha-MSH is under inhibitory control by dopamine would be the PIF and physiological MIF.