Accelerated atherosclerosis has become a complication of multiple autoimmune diseases, among which Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis stands out. The case of a patient with hypertension, diabetes, and chronic kidney disease of unknown etiology is described, who presented two acute coronary syndromes with a difference of only six months, with rapid progression of coronary involvement, in search of the etiology with an increase in inflammatory response markers, tomography with usual interstitial pneumonia and positive antibodies directed against myeloperoxidase (anti-MPO) that led to the diagnosis of microscopic polyangiitis (PAM). The situation in which a timely diagnostic suspicion is crucial since early treatment has a notable impact on the course and prognosis of the disease.

Endomyocardial fibrosis or Davies disease is a rare cause of restrictive cardiomyopathy. It is characterized by the deposit of fibrous material in the endocardium that leads to quickly progressive heart failure. It most frequently affects both ventricles, with isolated involvement of the right ventricle being the least common form. The clinical presentation of this entity is based on symptoms of right heart failure, although arrhythmias and conduction disorders may also be present. The treatment is determined by the management of congestion and surgical intervention in symptomatic patients. We present the first case of endomyocardial fibrosis isolated from the right ventricle in Colombia, we describe the clinical, etiological, imaging and management characteristics in order to deliver to the medical community an approximate understanding of this disease focusing on an unusual way...

Tuberculosis is a disease that is increasing and affects about 1/3 of the world’s population. In line with the increase in tuberculosis, cardiovascular disease has had a similar behavior to this group, ischemic coronary heart disease has become the main cause of death worldwide. It could be extracted, based on literature, a relationship between tuberculosis and ischemic coronary heart disease through risk factors in common and from a possible pathophysiological substrate that links them. The presentation of these two entities reported so far is varied: it has been found as a debut of an acute coronary syndrome in patients with active tuberculosis, and the progressive development of coronary atherosclerosis in patients with latent tuberculosis, among others. Given this possible link and the progressive increase in its incidence rates, we can affirm that we are facing an inadvertent synd...

La aterosclerosis acelerada se ha identificado como una complicación de múltiples enfermedadesautoinmunes, entre las que destacan las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilo (VAA). Se describe el caso de una paciente de 60 años, con antecedentes de hipertensión arterial , diabetes mellitus y enfermedad renal crónica de etiología no filiada, que presentó dos síndromes coronarios agudos con una diferencia de solo seis meses. Se evidenció rápida progresión del compromiso coronario, presencia de aumento de marcadores de respuesta inflamatoria, tomografía con neumonía intersticial usual y anticuerpos antimieloperoxidasa (anti-MPO) positivos que llevaron al diagnóstico de poliangitis microscópica (PAM). En estos casos, la sospecha diagnóstica oportuna es crucial, ya que el tratamiento temprano impacta de forma notable en el curso y pronóstico de la enf...

Objective.  Evaluate the change of lactate levels and its prognostic role in the postoperative period of patients undergoing pulmonary thromboendarterectomy. Methods. Retrospective study between 2001 and 2019. Patients older than 18 years and who underwent pulmonary thromboendarterectomy were included. The U Mann Whitney test was performed to evaluate the change between lactate levels, and Cox regression analysis to evaluate the relationship with mortality. Areas under the curve were constructed for lactate levels. Results. Seventy-three patients were operated on during the study period. Median age was 51 years, 55% female. The median lactate on days 1 was 4.65 mml/L and on day 2 it was 1.62 mml/L with a change of 2.87 mml/L. No differences were found between the levels measured on day 1 and 2 between the people who died and those who did not on day 30. In the multivariate regressio...

Objective.  Evaluate the change of lactate levels and its prognostic role in the postoperative period of patients undergoing pulmonary thromboendarterectomy. Methods. Retrospective study between 2001 and 2019. Patients older than 18 years and who underwent pulmonary thromboendarterectomy were included. The U Mann Whitney test was performed to evaluate the change between lactate levels, and Cox regression analysis to evaluate the relationship with mortality. Areas under the curve were constructed for lactate levels. Results. Seventy-three patients were operated on during the study period. Median age was 51 years, 55% female. The median lactate on days 1 was 4.65 mml/L and on day 2 it was 1.62 mml/L with a change of 2.87 mml/L. No differences were found between the levels measured on day 1 and 2 between the people who died and those who did not on day 30. In the multivariate regressio...