Accelerated atherosclerosis in anti-neutrophil cytoplasmic antibody-associated vasculitis: case report

• Autores: Uribe Ruíz, Natalia Andrea, Villa, María Paulina, Álzate Gutiérrez, Alberto, Saldarriaga Giraldo, Clara Inés, Thorrens Ríos, José Gregorio
• Formato: artículo
• Fecha de Publicación: 2024
• Institución: Instituto Nacional Cardiovascular
• Repositorio: Archivos peruanos de cardiología y cirugía cardiovascular
• Lenguaje: español; inglés
• OAI Identifier: oai:ojs.apcyccv.org.pe:article/331
• Enlace del recurso: https://apcyccv.org.pe/index.php/apccc/article/view/331
• Nivel de acceso: acceso abierto
• Materia: Aterosclerosis; Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos; Poliangitis Microscópica; Infarto del Miocardio; Atherosclerosis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Microscopic Polyangiitis; Myocardial Infarction

Accelerated atherosclerosis has become a complication of multiple autoimmune diseases, among which Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis stands out. The case of a patient with hypertension, diabetes, and chronic kidney disease of unknown etiology is described, who presented two acute coronary syndromes with a difference of only six months, with rapid progression of coronary involvement, in search of the etiology with an increase in inflammatory response markers, tomography with usual interstitial pneumonia and positive antibodies directed against myeloperoxidase (anti-MPO) that led to the diagnosis of microscopic polyangiitis (PAM). The situation in which a timely diagnostic suspicion is crucial since early treatment has a notable impact on the course and prognosis of the disease.