We report the case of a patient with Hemoglobin S / Thalassemia. It is feasible to recognize this infrequent disease by its clinical presentation and the aid of clinical laboratory . On this patient, the diagnosis was established based on the clinical findings, hematological evaluation (with careful observation of the red cell morphology and reticulocyte count) and electrophoretic analysis of hemoglobin. We discusse the physiopathology, clinical manifestations, treatment and alternative of prevention of this disease.

We report the case of a patient with several adverse effects, of fatal consequence, associated with drugs used in the treatment for Tuberculosis. Patient was hospitalized at the Hospital Nacional Arzobispo Loayza of Lima, Peru, since May until July 2001. We identified the presence of several adverse effects associated with antituberculosis drugs (dermatitis, nausea, vomit, interstitial nephritis, hepatitis for drug and thrombocytopenia, associated with Intracraneal hemorrhage, of fatal consequence). This study reports a case very infrequent in the world (including Peru), in relation with the presence of several adverse effects of antituberculosis drugs, in the same patient, who died because of these effects. We want to inform the potential risks associated with antituberculosis drugs (of great use in Peru for the high prevalence of Tuberculosis), that must have a regimen and adeq...