Introduction: Myrciaria dubia known as “camu camu” is a fruit that grows in the Amazon and its main characteristic is its high content of vitamin C. Ascorbic acid has a protective role in spermatogenesis as it is a compound that has excellent reducing action. The purpose of this research was to evaluate in vivo the cytoprotective capacity of the aqueous extract of the fruit of Myrciaria dubia (Kunth) McVaugh “camu-camu” against the mutagenic damage produced by the antineoplastic drug cyclophosphamide (CP) on the male germ line. Methodology: Mice (n= 60) were divided into five treatment groups: T1= negative control (without treatment); T2 ingested the aqueous extract (10mgkg-1), T3 ingested the aqueous extract (50mgkg-1), T4 ingested the aqueous extract (100mgkg-1); T5 is the positive control. All of them were injected with a single dose of CP (50 mgkg-1) intraperitoneally. Treatm...