ABSTRACT Introduction: Digestive bleeding can put patients’ lives at risk, even more so when the origin is not located in routine upper and lower endoscopy. The small intestine is the largest portion of the digestive tract and being a source of bleeding means a diagnostic and therapeutic medical challenge. Clinical case: We presented cases of two female patients, 53 and 60 years old, who develop digestive bleeding, locating its origin in the small bowel and undergoing surgical removal of the affected intestinal segment. The anatomopathological study finds malformed arteries and veins that communicate without an intermediate capillary bed. The diagnosis was arteriovenous malformation, a rare entity in the small bowel. Both cases are reviewed with emphasis on the histopathological criteria and their clinical correlation. Keywords: Arteriovenous malformation, small bowel, obscure digestiv...

Introduction: Hodgkin lymphomas are B-cell lymphoid neoplasms histologically characterized by a mixed inflammatory cellular component and few Hodgkin/Reed-Sternberg neoplastic cells. Classical Hodgkin Lymphoma (CHL) represents 10% of all lymphoma cases and 85% of all Hodgkin Lymphomas. According to the current World Health Organization classification, CHL is divided into 4 types: Nodular Sclerosing (NS), Mixed Cellularity (MC), Lymphocyte-Rich (LR), and Lymphocyte-Depleted (LD). Objetive: We reviewed all cases of Classical Hodgkin Lymphoma in the Pathological Anatomy Department at Edgardo Rebagliati Martins National Hospital during 2015 to 2019, in order to determine the most frequent type, the incidence according to age and gender, phenotypical characteristics and relation to Epstein Barr Virus (EBV). Materials and Methods:  We performed a retrospective descriptive case s...

ABSTRACT Introduction: Sarcina ventriculi is a Gram (+), anaerobic, non-motile cocci, with a fermentative carbohydrate metabolism, that survives and grows without problems in environments with acidic pH. It is a known etiological agent in veterinary pathology, however its pathogenic role in humans is controversial. In recent years, the finding of this microorganism in different anatomical places has been reported in humans with increasing frequency, predominantly in the upper digestive tract, mainly in the stomach, in patients with dyspepsia and/or delayed gastric emptying, some of these cases with serious evolution, even fatal. Clinical case: we report the case of a patient with dyspeptic symptoms, whose gastric biopsy identified Sarcina ventriculi and whose targeted pharmacological treatment ended the discomfort described. To the best of our knowledge, this is the first case reported i...

Introducción: El coriocarcinoma gástrico primario (CGP) es una neoplasia infrecuente y altamente agresiva que representa menos de 0.1% de todos los cánceres gástricos. Esta neoplasia suele ser frecuentemente confundida con adenocarcinoma gástrico debido a que comparte características clínicas, epidemiológicas e histopatológicas similares, por lo que es importante mantener una alta sospecha de esta entidad. Reporte de caso: Se presenta un el caso de una paciente mujer de 64 años que acudió al hospital con síntomas gastrointestinales inespecíficos que incluían anemia, fatiga y llenura precoz. La biopsia endoscópica de la lesión reveló la presencia de CGP en estadio clínico IV que presentó una respuesta parcial luego de 4 ciclos de quimioterapia con el esquema EMA/EP (Etoposido 140 mg, Metotrexate 440 mg, Actinomicina D 0.5 mg/ Etoposido 220 mg, cisplatino 110 mg). Conclu...

Introduction: Primary gastric choriocarcinoma (PGC) is a rare and highly aggressive neoplasm that represents less than 0.1% of all gastric cancers. This neoplasm is often confused with gastric adenocarcinoma because it shares clinical, epidemiological and histopathological characteristics, so it is important to maintain a high suspicion of this entity. Case of report: A case of a 64-year-old woman who came to the hospital with non-specific gastrointestinal symptoms that arose anemia, fatigue and early fullness is presented. The endoscopic biopsy of the lesion revealed the presence of PGC in clinical stage IV that presented a partial response after 4 cycles of chemotherapy with the EMA/EP regimen (Etoposide 140 mg, Methotrexate 440 mg, Actinomycin D 0.5 mg/ Etoposide 220 mg, cisplatin 110 mg). Conclusion: To emphasize the poor prognosis of extragonadal choriocarcinomas in contrast to gona...